Cargando…

CSConv2d: A 2-D Structural Convolution Neural Network with a Channel and Spatial Attention Mechanism for Protein-Ligand Binding Affinity Prediction

The binding affinity of small molecules to receptor proteins is essential to drug discovery and drug repositioning. Chemical methods are often time-consuming and costly, and models for calculating the binding affinity are imperative. In this study, we propose a novel deep learning method, namely CSC...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Xun, Liu, Dayan, Zhu, Jinfu, Rodriguez-Paton, Alfonso, Song, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145762/ https://www.ncbi.nlm.nih.gov/pubmed/33925310 http://dx.doi.org/10.3390/biom11050643

Ejemplares similares

SE-OnionNet: A Convolution Neural Network for Protein–Ligand Binding Affinity Prediction
por: Wang, Shudong, et al.
Publicado: (2021)

A Novel Method to Inspect 3D Ball Joint Socket Products Using 2D Convolutional Neural Network with Spatial and Channel Attention
por: Mustafaev, Bekhzod, et al.
Publicado: (2022)

Spatial Attention-Based 3D Graph Convolutional Neural Network for Sign Language Recognition
por: Al-Hammadi, Muneer, et al.
Publicado: (2022)

AK-Score: Accurate Protein-Ligand Binding Affinity Prediction Using an Ensemble of 3D-Convolutional Neural Networks
por: Kwon, Yongbeom, et al.
Publicado: (2020)

Sfcnn: a novel scoring function based on 3D convolutional neural network for accurate and stable protein–ligand affinity prediction
por: Wang, Yu, et al.
Publicado: (2022)

Multiscale Hybrid Convolutional Deep Neural Networks with Channel Attention
por: Yang, Hua, et al.
Publicado: (2022)

3D Convolutional Neural Networks Initialized from Pretrained 2D Convolutional Neural Networks for Classification of Industrial Parts
por: Merino, Ibon, et al.
Publicado: (2021)

Drug Response Prediction Based on 1D Convolutional Neural Network and Attention Mechanism
por: Mingxun, Zhu, et al.
Publicado: (2022)

Development of a graph convolutional neural network model for efficient prediction of protein-ligand binding affinities
por: Son, Jeongtae, et al.
Publicado: (2021)

An artificial intelligent diagnostic system on mobile Android terminals for cholelithiasis by lightweight convolutional neural network
por: Pang, Shanchen, et al.
Publicado: (2019)

DISTEMA: distance map-based estimation of single protein model accuracy with attentive 2D convolutional neural network
por: Chen, Xiao, et al.
Publicado: (2022)

Channel-Unet: A Spatial Channel-Wise Convolutional Neural Network for Liver and Tumors Segmentation
por: Chen, Yilong, et al.
Publicado: (2019)

OnionNet-2: A Convolutional Neural Network Model for Predicting Protein-Ligand Binding Affinity Based on Residue-Atom Contacting Shells
por: Wang, Zechen, et al.
Publicado: (2021)

2D Convolutional Neural Markov Models for Spatiotemporal Sequence Forecasting
por: Halim, Calvin Janitra, et al.
Publicado: (2020)

Sexing white 2D footprints using convolutional neural networks
por: Budka, Marcin, et al.
Publicado: (2021)

Classification with 2-D convolutional neural networks for breast cancer diagnosis
por: Sharma, Anuraganand, et al.
Publicado: (2022)

Wall segmentation in 2D images using convolutional neural networks
por: Bjekic, Mihailo, et al.
Publicado: (2023)

iEdgeDTA: integrated edge information and 1D graph convolutional neural networks for binding affinity prediction
por: Suviriyapaisal, Natchanon, et al.
Publicado: (2023)

Evaluation of 1D and 2D Deep Convolutional Neural Networks for Driving Event Recognition
por: Escottá, Álvaro Teixeira, et al.
Publicado: (2022)

DeepMHADTA: Prediction of Drug-Target Binding Affinity Using Multi-Head Self-Attention and Convolutional Neural Network
por: Deng, Lei, et al.
Publicado: (2022)

EnzyNet: enzyme classification using 3D convolutional neural networks on spatial representation
por: Amidi, Afshine, et al.
Publicado: (2018)

DeepDrug3D: Classification of ligand-binding pockets in proteins with a convolutional neural network
por: Pu, Limeng, et al.
Publicado: (2019)

DC-CNN: Dual-channel Convolutional Neural Networks with attention-pooling for fake news detection
por: Ma, Kun, et al.
Publicado: (2022)

Light-efficient channel attention in convolutional neural networks for tic recognition in the children with tic disorders
por: Geng, Fudi, et al.
Publicado: (2022)

Multiscale Convolutional Neural Network Based on Channel Space Attention for Gearbox Compound Fault Diagnosis
por: Xu, Qinghong, et al.
Publicado: (2023)

Hybrid convolution neural network with channel attention mechanism for sensor-based human activity recognition
por: Mekruksavanich, Sakorn, et al.
Publicado: (2023)

Real-time guava tree-part segmentation using fully convolutional network with channel and spatial attention
por: Lin, Guichao, et al.
Publicado: (2022)

A Cascade Graph Convolutional Network for Predicting Protein–Ligand Binding Affinity
por: Shen, Huimin, et al.
Publicado: (2021)

A 3D-2D Convolutional Neural Network and Transfer Learning for Hyperspectral Image Classification
por: Nyabuga, Douglas Omwenga, et al.
Publicado: (2021)

Automatic snoring detection using a hybrid 1D–2D convolutional neural network
por: Li, Ruixue, et al.
Publicado: (2023)

Convolutional neural networks for detection of transthyretin amyloidosis in 2D scintigraphy images
por: Halme, Hanna-Leena, et al.
Publicado: (2022)

Detecting positional vertigo using an ensemble of 2D convolutional neural networks()
por: Newman, Jacob L., et al.
Publicado: (2021)

Convolutional Neural Network Model Based on 2D Fingerprint for Bioactivity Prediction
por: Hentabli, Hamza, et al.
Publicado: (2022)

CYP 2D6 Binding Affinity Predictions Using Multiple Ligand and Protein Conformations
por: Perić-Hassler, Lovorka, et al.
Publicado: (2013)

OnionNet: a Multiple-Layer Intermolecular-Contact-Based Convolutional Neural Network for Protein–Ligand Binding Affinity Prediction
por: Zheng, Liangzhen, et al.
Publicado: (2019)

Accelerating 3D Convolutional Neural Network with Channel Bottleneck Module for EEG-Based Emotion Recognition
por: Kim, Sungkyu, et al.
Publicado: (2022)

Posture Detection of Individual Pigs Based on Lightweight Convolution Neural Networks and Efficient Channel-Wise Attention
por: Luo, Yizhi, et al.
Publicado: (2021)

Classification of Amino Acids Using Hybrid Terahertz Spectrum and an Efficient Channel Attention Convolutional Neural Network
por: Wang, Bo, et al.
Publicado: (2022)

Binding affinity predictions with hybrid quantum-classical convolutional neural networks
por: Domingo, L., et al.
Publicado: (2023)

Shot Boundary Detection with 3D Depthwise Convolutions and Visual Attention
por: Esteve Brotons, Miguel Jose, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_iklkd9n4l3n680v46nsog6s0v9