Triphenilphosphonium Analogs of Chloramphenicol as Dual-Acting Antimicrobial and Antiproliferating Agents

In the current work, in continuation of our recent research, we synthesized and studied new chimeric compounds, including the ribosome-targeting antibiotic chloramphenicol (CHL) and the membrane-penetrating cation triphenylphosphonium (TPP), which are linked by alkyl groups of different lengths. Usi...

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Detalles Bibliográficos
Autores principales: Pavlova, Julia A., Khairullina, Zimfira Z., Tereshchenkov, Andrey G., Nazarov, Pavel A., Lukianov, Dmitrii A., Volynkina, Inna A., Skvortsov, Dmitry A., Makarov, Gennady I., Abad, Etna, Murayama, Somay Y., Kajiwara, Susumu, Paleskava, Alena, Konevega, Andrey L., Antonenko, Yuri N., Lyakhovich, Alex, Osterman, Ilya A., Bogdanov, Alexey A., Sumbatyan, Natalia V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145938/
https://www.ncbi.nlm.nih.gov/pubmed/33922611
http://dx.doi.org/10.3390/antibiotics10050489

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