Catalytic asymmetric hydrogenation of (Z)-α-dehydroamido boronate esters: direct route to alkyl-substituted α-amidoboronic esters

The direct catalytic asymmetric hydrogenation of (Z)-α-dehydroamino boronate esters was realized. Using this approach, a class of therapeutically relevant alkyl-substituted α-amidoboronic esters was easily synthesized in high yields with generally excellent enantioselectivities (up to 99% yield and...

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Detalles Bibliográficos
Autores principales: Lou, Yazhou, Wang, Jun, Gong, Gelin, Guan, Fanfu, Lu, Jiaxiang, Wen, Jialin, Zhang, Xumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146211/
https://www.ncbi.nlm.nih.gov/pubmed/34123062
http://dx.doi.org/10.1039/c9sc04534a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146211/
https://www.ncbi.nlm.nih.gov/pubmed/34123062
http://dx.doi.org/10.1039/c9sc04534a

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