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Involvement of TLR4 signaling regulated-COX2/PGE2 axis in liver fibrosis induced by Schistosoma japonicum infection

BACKGROUND: Hepatic stellate cell (HSC) activation plays a pivotal role in hepatic inflammation and liver fibrosis. TLR4 pathway activation has been reported to be involved in mice liver fibrosis induced by hepatitis virus infection, alcohol abuse, biliary ligation, carbon tetrachloride 4 treatment,...

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Detalles Bibliográficos
Autores principales: Chen, Lan, Ji, Xiaofang, Wang, Manni, Liao, Xiaoyan, Liang, Cuiying, Tang, Juanjuan, Wen, Zhencheng, Dominique, Ferrandon, Li, Zi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146234/
https://www.ncbi.nlm.nih.gov/pubmed/34034779
http://dx.doi.org/10.1186/s13071-021-04790-7

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