Dandelion flower-like micelles

Dandelion flower-like micelles (DFMs) were prepared by self-assembly of polycaprolactone (PCL) functionalized surface cross-linked micelles (SCMs). Upon reductive stimuli, the SCMs can be released from the DFMs by non-Brownian motion at an average speed of 19.09 μm s(−1). Similar to the property of...

Descripción completa

Detalles Bibliográficos
Autores principales: Yao, Yongchao, Xu, Deqiu, Zhu, Yuhong, Dai, Xin, Yu, Yunlong, Luo, Jianbin, Zhang, Shiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146335/
https://www.ncbi.nlm.nih.gov/pubmed/34123049
http://dx.doi.org/10.1039/c9sc05741b
_version_ 1783697373103390720
author Yao, Yongchao
Xu, Deqiu
Zhu, Yuhong
Dai, Xin
Yu, Yunlong
Luo, Jianbin
Zhang, Shiyong
author_facet Yao, Yongchao
Xu, Deqiu
Zhu, Yuhong
Dai, Xin
Yu, Yunlong
Luo, Jianbin
Zhang, Shiyong
author_sort Yao, Yongchao
collection PubMed
description Dandelion flower-like micelles (DFMs) were prepared by self-assembly of polycaprolactone (PCL) functionalized surface cross-linked micelles (SCMs). Upon reductive stimuli, the SCMs can be released from the DFMs by non-Brownian motion at an average speed of 19.09 μm s(−1). Similar to the property of dandelion flowers dispersing their seeds over a long distance, the DFMs demonstrated enhanced multicellular tumor spheroid (MTS) penetration, a useful property in the treatment of many diseases including cancer, infection-of-biofilm diseases and ocular problems.
format Online
Article
Text
id pubmed-8146335
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher The Royal Society of Chemistry
record_format MEDLINE/PubMed
spelling pubmed-81463352021-06-11 Dandelion flower-like micelles Yao, Yongchao Xu, Deqiu Zhu, Yuhong Dai, Xin Yu, Yunlong Luo, Jianbin Zhang, Shiyong Chem Sci Chemistry Dandelion flower-like micelles (DFMs) were prepared by self-assembly of polycaprolactone (PCL) functionalized surface cross-linked micelles (SCMs). Upon reductive stimuli, the SCMs can be released from the DFMs by non-Brownian motion at an average speed of 19.09 μm s(−1). Similar to the property of dandelion flowers dispersing their seeds over a long distance, the DFMs demonstrated enhanced multicellular tumor spheroid (MTS) penetration, a useful property in the treatment of many diseases including cancer, infection-of-biofilm diseases and ocular problems. The Royal Society of Chemistry 2019-12-03 /pmc/articles/PMC8146335/ /pubmed/34123049 http://dx.doi.org/10.1039/c9sc05741b Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Yao, Yongchao
Xu, Deqiu
Zhu, Yuhong
Dai, Xin
Yu, Yunlong
Luo, Jianbin
Zhang, Shiyong
Dandelion flower-like micelles
title Dandelion flower-like micelles
title_full Dandelion flower-like micelles
title_fullStr Dandelion flower-like micelles
title_full_unstemmed Dandelion flower-like micelles
title_short Dandelion flower-like micelles
title_sort dandelion flower-like micelles
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146335/
https://www.ncbi.nlm.nih.gov/pubmed/34123049
http://dx.doi.org/10.1039/c9sc05741b
work_keys_str_mv AT yaoyongchao dandelionflowerlikemicelles
AT xudeqiu dandelionflowerlikemicelles
AT zhuyuhong dandelionflowerlikemicelles
AT daixin dandelionflowerlikemicelles
AT yuyunlong dandelionflowerlikemicelles
AT luojianbin dandelionflowerlikemicelles
AT zhangshiyong dandelionflowerlikemicelles

Ejemplares similares