Substrate Stiffness and Stretch Regulate Profibrotic Mechanosignaling in Pulmonary Arterial Adventitial Fibroblasts

Pulmonary arterial adventitial fibroblasts (PAAFs) are important regulators of fibrotic vascular remodeling during the progression of pulmonary arterial hypertension (PAH), a disease that currently has no effective anti-fibrotic treatments. We conducted in-vitro experiments in PAAFs cultured on hydr...

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Detalles Bibliográficos
Autores principales: Wang, Ariel, Cao, Shulin, Stowe, Jennifer C., Valdez-Jasso, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146344/
https://www.ncbi.nlm.nih.gov/pubmed/33922850
http://dx.doi.org/10.3390/cells10051000

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146344/
https://www.ncbi.nlm.nih.gov/pubmed/33922850
http://dx.doi.org/10.3390/cells10051000

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