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Adverse Events of Mind-Body Interventions in Children: A Systematic Review

Mind-body interventions (MBIs) are one of the top ten complementary approaches utilized in pediatrics, but there is limited knowledge on associated adverse events (AE). The objective of this review was to systematically review AEs reported in association with MBIs in children. In this systematic rev...

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Autores principales: Lyszczyk, Meagan, Karkhaneh, Mohammad, Gladwin, Kerri Kaiser, Funabashi, Martha, Zorzela, Liliane, Vohra, Sunita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146392/
https://www.ncbi.nlm.nih.gov/pubmed/33947033
http://dx.doi.org/10.3390/children8050358
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author Lyszczyk, Meagan
Karkhaneh, Mohammad
Gladwin, Kerri Kaiser
Funabashi, Martha
Zorzela, Liliane
Vohra, Sunita
author_facet Lyszczyk, Meagan
Karkhaneh, Mohammad
Gladwin, Kerri Kaiser
Funabashi, Martha
Zorzela, Liliane
Vohra, Sunita
author_sort Lyszczyk, Meagan
collection PubMed
description Mind-body interventions (MBIs) are one of the top ten complementary approaches utilized in pediatrics, but there is limited knowledge on associated adverse events (AE). The objective of this review was to systematically review AEs reported in association with MBIs in children. In this systematic review the electronic databases MEDLINE, Embase, CINAHL, CDSR, and CCRCT were searched from inception to August 2018. We included primary studies on participants ≤ 21 years of age that used an MBI. Experimental studies were assessed for whether AEs were reported on or not, and all other study designs were included only if they reported an AE. A total of 441 were included as primary pediatric MBI studies. Of these, 377 (85.5%) did not explicitly report the presence/absence of AEs or a safety assessment. There were 64 included studies: 43 experimental studies reported that no AE occurred, and 21 studies reported AEs. There were 37 AEs found, of which the most serious were grade 3. Most of the studies reporting AEs did not report on severity (81.0%) or duration of AEs (52.4%). MBIs are popularly used in children; however associated harms are often not reported and lack important information for meaningful assessment.
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spelling pubmed-81463922021-05-26 Adverse Events of Mind-Body Interventions in Children: A Systematic Review Lyszczyk, Meagan Karkhaneh, Mohammad Gladwin, Kerri Kaiser Funabashi, Martha Zorzela, Liliane Vohra, Sunita Children (Basel) Review Mind-body interventions (MBIs) are one of the top ten complementary approaches utilized in pediatrics, but there is limited knowledge on associated adverse events (AE). The objective of this review was to systematically review AEs reported in association with MBIs in children. In this systematic review the electronic databases MEDLINE, Embase, CINAHL, CDSR, and CCRCT were searched from inception to August 2018. We included primary studies on participants ≤ 21 years of age that used an MBI. Experimental studies were assessed for whether AEs were reported on or not, and all other study designs were included only if they reported an AE. A total of 441 were included as primary pediatric MBI studies. Of these, 377 (85.5%) did not explicitly report the presence/absence of AEs or a safety assessment. There were 64 included studies: 43 experimental studies reported that no AE occurred, and 21 studies reported AEs. There were 37 AEs found, of which the most serious were grade 3. Most of the studies reporting AEs did not report on severity (81.0%) or duration of AEs (52.4%). MBIs are popularly used in children; however associated harms are often not reported and lack important information for meaningful assessment. MDPI 2021-04-29 /pmc/articles/PMC8146392/ /pubmed/33947033 http://dx.doi.org/10.3390/children8050358 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Lyszczyk, Meagan
Karkhaneh, Mohammad
Gladwin, Kerri Kaiser
Funabashi, Martha
Zorzela, Liliane
Vohra, Sunita
Adverse Events of Mind-Body Interventions in Children: A Systematic Review
title Adverse Events of Mind-Body Interventions in Children: A Systematic Review
title_full Adverse Events of Mind-Body Interventions in Children: A Systematic Review
title_fullStr Adverse Events of Mind-Body Interventions in Children: A Systematic Review
title_full_unstemmed Adverse Events of Mind-Body Interventions in Children: A Systematic Review
title_short Adverse Events of Mind-Body Interventions in Children: A Systematic Review
title_sort adverse events of mind-body interventions in children: a systematic review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146392/
https://www.ncbi.nlm.nih.gov/pubmed/33947033
http://dx.doi.org/10.3390/children8050358
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