Neuronal and Astrocytic Extracellular Vesicle Biomarkers in Blood Reflect Brain Pathology in Mouse Models of Alzheimer’s Disease

Circulating neuronal extracellular vesicles (NEVs) of Alzheimer’s disease (AD) patients show high Tau and β-amyloid (Aβ) levels, whereas their astrocytic EVs (AEVs) contain high complement levels. To validate EV proteins as AD biomarkers, we immunocaptured NEVs and AEVs from plasma collected from fi...

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Detalles Bibliográficos
Autores principales: Delgado-Peraza, Francheska, Nogueras-Ortiz, Carlos J., Volpert, Olga, Liu, Dong, Goetzl, Edward J., Mattson, Mark P., Greig, Nigel H., Eitan, Erez, Kapogiannis, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146429/
https://www.ncbi.nlm.nih.gov/pubmed/33922642
http://dx.doi.org/10.3390/cells10050993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146429/
https://www.ncbi.nlm.nih.gov/pubmed/33922642
http://dx.doi.org/10.3390/cells10050993

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