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CpG Methylation Profiles of HIV-1 Proviral DNA in Individuals on ART

The latent HIV-1 reservoir is comprised of stably integrated and intact proviruses with limited to no viral transcription. It has been proposed that latent infection may be maintained by methylation of pro-viral DNA. Here, for the first time, we investigate the cytosine methylation of a replication...

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Detalles Bibliográficos
Autores principales: Boltz, Valerie F., Ceriani, Cristina, Rausch, Jason W., Shao, Wei, Bale, Michael J., Keele, Brandon F., Hoh, Rebecca, Milush, Jeffrey M., Deeks, Steve G., Maldarelli, Frank, Kearney, Mary F., Coffin, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146454/
https://www.ncbi.nlm.nih.gov/pubmed/33946976
http://dx.doi.org/10.3390/v13050799