Selection Criteria of Cord Blood Units for Platelet Gel Production: Proposed Directions from Hellenic Cord Blood Bank. Comment on Mallis et al. Short Term Results of Fibrin Gel Obtained from Cord Blood Units: A Preliminary in Vitro Study. Bioengineering 2019, 6, 66

This article provides additional knowledge for cord blood platelet gel (CBPG) production. Recently, it has been shown that CBPG exerts beneficial properties in wound healing applications. CBPG is produced after a two-step centrifugation process, following the addition of calcium gluconate. Clinical-...

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Detalles Bibliográficos
Autores principales: Mallis, Panagiotis, Michalopoulos, Efstathios, Panagouli, Effrosyni, Dimou, Zetta, Sarri, Eirini Faidra, Georgiou, Eleni, Gkioka, Vasiliki, Stavropoulos-Giokas, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146526/
https://www.ncbi.nlm.nih.gov/pubmed/33925496
http://dx.doi.org/10.3390/bioengineering8050053
Descripción
Sumario:This article provides additional knowledge for cord blood platelet gel (CBPG) production. Recently, it has been shown that CBPG exerts beneficial properties in wound healing applications. CBPG is produced after a two-step centrifugation process, following the addition of calcium gluconate. Clinical-grade CBPG can be produced in public cord blood banks, worldwide. However, standardization of the CBPG production process must be established in order to reduce discrepancies that occurred due to different platelet gel preparations. This article aims to provide an update regarding the selection criteria of cord blood units (CBUs), and to provide evidence for the improvement of the CBPG production process. (Comment on “Short Term Results of Fibrin Gel Obtained from Cord Blood Units: A Preliminary in Vitro Study” Bioengineering 2019, 6, 66).

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