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Supercritical CO(2) Extraction of Organic Solvents from Flunisolide and Fluticasone Propionate
In this work, Class 2 and Class 3 solvents contained in two corticosteroids, flunisolide (Fluni) and fluticasone propionate (Fluti), were reduced to a few ppm by supercritical CO(2) extraction. The process was carried out at pressures from 80 to 200 bar, temperatures of 40 °C and 80 °C, and at a fix...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146547/ https://www.ncbi.nlm.nih.gov/pubmed/33922659 http://dx.doi.org/10.3390/pharmaceutics13050612 |