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Total synthesis of (−)-penicimutanin a and related congeners

The first total synthesis of penicimutanin A (1) was achieved within 10 steps (LLS). Key innovations in this synthesis consist of (1) a highly efficient electro-oxidative dearomatization; (2) an unprecedented bisoxirane-directed intermolecular aldol reaction from the sterically hindered face of the...

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Detalles Bibliográficos
Autores principales: Yu, Haiyong, Zong, Yan, Xu, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146686/
https://www.ncbi.nlm.nih.gov/pubmed/34123037
http://dx.doi.org/10.1039/c9sc05252f

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