Cargando…
Antioxidant Synergy of Mitochondrial Phospholipase PNPLA8/iPLA2γ with Fatty Acid–Conducting SLC25 Gene Family Transporters
Patatin-like phospholipase domain-containing protein PNPLA8, also termed Ca(2+)-independent phospholipase A2γ (iPLA2γ), is addressed to the mitochondrial matrix (or peroxisomes), where it may manifest its unique activity to cleave phospholipid side-chains from both sn-1 and sn-2 positions, consequen...
Autores principales: | Jabůrek, Martin, Průchová, Pavla, Holendová, Blanka, Galkin, Alexander, Ježek, Petr |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146845/ https://www.ncbi.nlm.nih.gov/pubmed/33926059 http://dx.doi.org/10.3390/antiox10050678 |
Ejemplares similares
-
Antioxidant Role and Cardiolipin Remodeling by Redox-Activated Mitochondrial Ca(2+)-Independent Phospholipase A(2)γ in the Brain
por: Průchová, Pavla, et al.
Publicado: (2022) -
H(2)O(2)-Activated Mitochondrial Phospholipase iPLA(2)γ Prevents Lipotoxic Oxidative Stress in Synergy with UCP2, Amplifies Signaling via G-Protein–Coupled Receptor GPR40, and Regulates Insulin Secretion in Pancreatic β-Cells
por: Ježek, Jan, et al.
Publicado: (2015) -
Mitochondrial Uncoupling Proteins: Subtle Regulators of Cellular Redox Signaling
por: Ježek, Petr, et al.
Publicado: (2018) -
Fatty Acid-Stimulated Insulin Secretion vs. Lipotoxicity
por: Ježek, Petr, et al.
Publicado: (2018) -
Phospholipase iPLA2β acts as a guardian against ferroptosis
por: Mao, Chao, et al.
Publicado: (2021)