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Preoperative Devascularization of Choroid Plexus Tumors: Specific Issues about Anatomy and Embolization Technique

(1) Background: Surgical treatment of choroid plexus tumors is challenging, burdened by a notable risk of bleeding. Neoadjuvant chemotherapy and preoperative embolization have been attempted, with encouraging results; however, the consensus on these procedures is lacking. (2) Methods: We present a c...

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Autores principales: Baro, Valentina, Gabrieli, Joseph Domenico, Cester, Giacomo, D’Errico, Ignazio, Landi, Andrea, Denaro, Luca, Causin, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146914/
https://www.ncbi.nlm.nih.gov/pubmed/33922937
http://dx.doi.org/10.3390/brainsci11050540
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author Baro, Valentina
Gabrieli, Joseph Domenico
Cester, Giacomo
D’Errico, Ignazio
Landi, Andrea
Denaro, Luca
Causin, Francesco
author_facet Baro, Valentina
Gabrieli, Joseph Domenico
Cester, Giacomo
D’Errico, Ignazio
Landi, Andrea
Denaro, Luca
Causin, Francesco
author_sort Baro, Valentina
collection PubMed
description (1) Background: Surgical treatment of choroid plexus tumors is challenging, burdened by a notable risk of bleeding. Neoadjuvant chemotherapy and preoperative embolization have been attempted, with encouraging results; however, the consensus on these procedures is lacking. (2) Methods: We present a case of a 10-month-old girl who underwent preoperative embolization of a hemorrhagic choroid plexus carcinoma of the lateral ventricle via the anterior choroidal artery, followed by total resection. (3) Results: The endovascular procedure was successfully completed, despite the rectification of the anterior choroidal artery associated with the absence of flow proximal to the plexal point. Minimal bleeding was observed during resection and the patient remained neurologically intact. (4) Conclusions: The time from entrance to exit in the anterior choroidal artery should be monitored and regarded as a potential ‘occlusion time’ in this specific group of patients. Nevertheless, our case supports the feasibility and effectiveness of preoperative embolization of a choroid plexus carcinoma of the lateral ventricle via the anterior choroidal artery, without complications. Furthermore, we suggest the use of a fast-embolic agent, such as N-butyl cyanoacrylate glue, as the preferred agent for this specific pathology and patient population.
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spelling pubmed-81469142021-05-26 Preoperative Devascularization of Choroid Plexus Tumors: Specific Issues about Anatomy and Embolization Technique Baro, Valentina Gabrieli, Joseph Domenico Cester, Giacomo D’Errico, Ignazio Landi, Andrea Denaro, Luca Causin, Francesco Brain Sci Case Report (1) Background: Surgical treatment of choroid plexus tumors is challenging, burdened by a notable risk of bleeding. Neoadjuvant chemotherapy and preoperative embolization have been attempted, with encouraging results; however, the consensus on these procedures is lacking. (2) Methods: We present a case of a 10-month-old girl who underwent preoperative embolization of a hemorrhagic choroid plexus carcinoma of the lateral ventricle via the anterior choroidal artery, followed by total resection. (3) Results: The endovascular procedure was successfully completed, despite the rectification of the anterior choroidal artery associated with the absence of flow proximal to the plexal point. Minimal bleeding was observed during resection and the patient remained neurologically intact. (4) Conclusions: The time from entrance to exit in the anterior choroidal artery should be monitored and regarded as a potential ‘occlusion time’ in this specific group of patients. Nevertheless, our case supports the feasibility and effectiveness of preoperative embolization of a choroid plexus carcinoma of the lateral ventricle via the anterior choroidal artery, without complications. Furthermore, we suggest the use of a fast-embolic agent, such as N-butyl cyanoacrylate glue, as the preferred agent for this specific pathology and patient population. MDPI 2021-04-25 /pmc/articles/PMC8146914/ /pubmed/33922937 http://dx.doi.org/10.3390/brainsci11050540 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Baro, Valentina
Gabrieli, Joseph Domenico
Cester, Giacomo
D’Errico, Ignazio
Landi, Andrea
Denaro, Luca
Causin, Francesco
Preoperative Devascularization of Choroid Plexus Tumors: Specific Issues about Anatomy and Embolization Technique
title Preoperative Devascularization of Choroid Plexus Tumors: Specific Issues about Anatomy and Embolization Technique
title_full Preoperative Devascularization of Choroid Plexus Tumors: Specific Issues about Anatomy and Embolization Technique
title_fullStr Preoperative Devascularization of Choroid Plexus Tumors: Specific Issues about Anatomy and Embolization Technique
title_full_unstemmed Preoperative Devascularization of Choroid Plexus Tumors: Specific Issues about Anatomy and Embolization Technique
title_short Preoperative Devascularization of Choroid Plexus Tumors: Specific Issues about Anatomy and Embolization Technique
title_sort preoperative devascularization of choroid plexus tumors: specific issues about anatomy and embolization technique
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146914/
https://www.ncbi.nlm.nih.gov/pubmed/33922937
http://dx.doi.org/10.3390/brainsci11050540
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