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Stem Cell-Derived Viral Antigen-Specific T Cells Suppress HIV Replication and PD-1 Expression on CD4+ T Cells
The viral antigen (Ag)-specific CD8+ cytotoxic T lymphocytes (CTLs) derived from pluripotent stem cells (PSCs), i.e., PSC-CTLs, have the ability to suppress the human immunodeficiency virus (HIV) infection. After adoptive transfer, PSC-CTLs can infiltrate into the local tissues to suppress HIV repli...
Autores principales: | Haque, Mohammad, Lei, Fengyang, Xiong, Xiaofang, Ren, Yijie, Peng, Hao-Yun, Wang, Liqing, Kumar, Anil, Das, Jugal Kishore, Song, Jianxun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146941/ https://www.ncbi.nlm.nih.gov/pubmed/33923025 http://dx.doi.org/10.3390/v13050753 |
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