A Nanoscaffolded Spike-RBD Vaccine Provides Protection against SARS-CoV-2 with Minimal Anti-Scaffold Response

The response of the adaptive immune system is augmented by multimeric presentation of a specific antigen, resembling viral particles. Several vaccines have been designed based on natural or designed protein scaffolds, which exhibited a potent adaptive immune response to antigens; however, antibodies...

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Detalles Bibliográficos
Autores principales: Lainšček, Duško, Fink, Tina, Forstnerič, Vida, Hafner-Bratkovič, Iva, Orehek, Sara, Strmšek, Žiga, Manček-Keber, Mateja, Pečan, Peter, Esih, Hana, Malenšek, Špela, Aupič, Jana, Dekleva, Petra, Plaper, Tjaša, Vidmar, Sara, Kadunc, Lucija, Benčina, Mojca, Omersa, Neža, Anderluh, Gregor, Pojer, Florence, Lau, Kelvin, Hacker, David, Correia, Bruno E., Peterhoff, David, Wagner, Ralf, Bergant, Valter, Herrmann, Alexander, Pichlmair, Andreas, Jerala, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146944/
https://www.ncbi.nlm.nih.gov/pubmed/33925446
http://dx.doi.org/10.3390/vaccines9050431

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