Cargando…

Regulation of Cardiac Conduction and Arrhythmias by Ankyrin/Spectrin-Based Macromolecular Complexes

The cardiac conduction system is an extended network of excitable tissue tasked with generation and propagation of electrical impulses to signal coordinated contraction of the heart. The fidelity of this system depends on the proper spatio-temporal regulation of ion channels in myocytes throughout t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nassal, Drew, Yu, Jane, Min, Dennison, Lane, Cemantha, Shaheen, Rebecca, Gratz, Daniel, Hund, Thomas J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146975/ https://www.ncbi.nlm.nih.gov/pubmed/33946725 http://dx.doi.org/10.3390/jcdd8050048

Ejemplares similares

Spectrin-Based Regulation of Cardiac Fibroblast Cell-Cell Communication
por: Nassal, Drew M., et al.
Publicado: (2023)

Ca(2+)/calmodulin kinase II–dependent regulation of β(IV)-spectrin modulates cardiac fibroblast gene expression, proliferation, and contractility
por: Nassal, Drew M., et al.
Publicado: (2021)

Ankyrins and Spectrins in Cardiovascular Biology and Disease
por: El Refaey, Mona M., et al.
Publicado: (2017)

Spectrin functions upstream of ankyrin in a spectrin cytoskeleton assembly pathway
por: Das, Amlan, et al.
Publicado: (2006)

Giant ankyrin-G regulates cardiac function
por: Cavus, Omer, et al.
Publicado: (2021)

A HIERARCHY OF ANKYRIN/SPECTRIN COMPLEXES CLUSTERS SODIUM CHANNELS AT NODES OF RANVIER
por: Ho, Tammy Szu-Yu, et al.
Publicado: (2014)

Challenges and Opportunities for Therapeutic Targeting of Calmodulin Kinase II in Heart
por: Nassal, Drew, et al.
Publicado: (2020)

Isoforms of Spectrin and Ankyrin Reflect the Functional Topography of the Mouse Kidney
por: Stankewich, Michael C., et al.
Publicado: (2016)

Ankyrin binds to the 15th repetitive unit of erythroid and nonerythroid beta-spectrin
Publicado: (1991)

Dynamic properties of ankyrin in T lymphocytes: colocalization with spectrin and protein kinase C beta
Publicado: (1994)

Tissue-specific expression of distinct spectrin and ankyrin transcripts in erythroid and nonerythroid cells
Publicado: (1985)

T-type calcium channels functionally interact with spectrin (α/β) and ankyrin B
por: Garcia-Caballero, Agustin, et al.
Publicado: (2018)

βIV spectrin is recruited to axon initial segments and nodes of Ranvier by ankyrinG
por: Yang, Yang, et al.
Publicado: (2007)

Posttranslational control of membrane-skeleton (ankyrin and alpha beta- spectrin) assembly in early myogenesis
Publicado: (1985)

Dynamic spectrin/ankyrin-G microdomains promote lateral membrane assembly by opposing endocytosis
por: Jenkins, Paul M., et al.
Publicado: (2015)

Spherocytosis-Related L1340P Mutation in Ankyrin Affects Its Interactions with Spectrin
por: Machnicka, Beata, et al.
Publicado: (2023)

α-synuclein promotes neuronal dysfunction and death by disrupting the binding of ankyrin to ß-spectrin
por: Maor, Gali, et al.
Publicado: (2023)

Phospho-ablation of cardiac sodium channel Na(v)1.5 mitigates susceptibility to atrial fibrillation and improves glucose homeostasis under conditions of diet-induced obesity
por: Dewal, Revati S., et al.
Publicado: (2021)

Biogenesis of the avian erythroid membrane skeleton: receptor-mediated assembly and stabilization of ankyrin (goblin) and spectrin
Publicado: (1984)

Molecular mechanisms that enhance synapse stability despite persistent disruption of the spectrin/ankyrin/microtubule cytoskeleton
por: Massaro, Catherine M., et al.
Publicado: (2009)

Ankyrin-G palmitoylation and βII-spectrin binding to phosphoinositide lipids drive lateral membrane assembly
por: He, Meng, et al.
Publicado: (2014)

β-Spectrin Is Colocalized with Both Voltage-gated Sodium Channels and Ankyrin(G) at the Adult Rat Neuromuscular Junction
por: Wood, S.J., et al.
Publicado: (1998)

Key Amino Acid Residues of Ankyrin-Sensitive Phosphatidylethanolamine/Phosphatidylcholine-Lipid Binding Site of βI-Spectrin
por: Wolny, Marcin, et al.
Publicado: (2011)

βIV-spectrin regulates sodium channel clustering through ankyrin-G at axon initial segments and nodes of Ranvier
por: Komada, Masayuki, et al.
Publicado: (2002)

Ankyrin-B Interactions with Spectrin and Dynactin-4 Are Required for Dystrophin-based Protection of Skeletal Muscle from Exercise Injury
por: Ayalon, Gai, et al.
Publicado: (2011)

The effect of the lipid-binding site of the ankyrin-binding domain of erythroid β-spectrin on the properties of natural membranes and skeletal structures
por: Chorzalska, Anna, et al.
Publicado: (2010)

Golgi spectrin: identification of an erythroid beta-spectrin homolog associated with the Golgi complex
Publicado: (1994)

Transgene Rescue Identifies an Essential Function for Drosophila β Spectrin in the Nervous System and a Selective Requirement for Ankyrin-2–binding Activity
por: Mazock, G. Harper, et al.
Publicado: (2010)

Novel Mechanistic Roles for Ankyrin-G in Cardiac Remodeling and Heart Failure
por: Makara, Michael A., et al.
Publicado: (2018)

Management of cardiac conduction abnormalities and arrhythmia in aircrew
por: Guettler, Norbert, et al.
Publicado: (2019)

β-III spectrin underpins ankyrin R function in Purkinje cell dendritic trees: protein complex critical for sodium channel activity is impaired by SCA5-associated mutations
por: Clarkson, Yvonne L., et al.
Publicado: (2014)

Identification of a small cytoplasmic ankyrin (AnkG119) in the kidney and muscle that binds beta I sigma spectrin and associates with the Golgi apparatus
Publicado: (1996)

LongQt: A cardiac electrophysiology simulation platform
por: Onal, Birce, et al.
Publicado: (2016)

Defects in Cytoskeletal Signaling Pathways, Arrhythmia, and Sudden Cardiac Death
por: Smith, Sakima, et al.
Publicado: (2012)

Impact of stress on cardiac phenotypes in mice harboring an ankyrin-B disease variant
por: Wallace, Michael J., et al.
Publicado: (2023)

Spectrin is peripheral
por: Bonetta, Laura
Publicado: (2005)

Ankyrin-G coordinates assembly of the spectrin-based membrane skeleton, voltage-gated sodium channels, and L1 CAMs at Purkinje neuron initial segments
por: Jenkins, Scott M., et al.
Publicado: (2001)

β spectrin-dependent and domain specific mechanisms for Na(+) channel clustering
por: Liu, Cheng-Hsin, et al.
Publicado: (2020)

Nodal β spectrins are required to maintain Na(+) channel clustering and axon integrity
por: Liu, Cheng-Hsin, et al.
Publicado: (2020)

Avian lens spectrin: subunit composition compared with erythrocyte and brain spectrin
Publicado: (1983)

Cannot write session to /tmp/vufind_sessions/sess_ivbvn74rv60fsfa14tqr61kgjh