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Different Chronic Disorders That Fall within the Term Juvenile Idiopathic Arthritis
Juvenile idiopathic arthritis (JIA) represents a significant challenge for pediatricians who intend to diagnose and treat this pathology. The classification criteria for JIA subtypes are rigid and often do not fully satisfy the possibilities of classification in the subtype. The objective of this st...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146979/ https://www.ncbi.nlm.nih.gov/pubmed/33925491 http://dx.doi.org/10.3390/life11050398 |
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author | Sur, Lucia M. Gaga, Remus Duca, Emanuela Sur, Genel Lupan, Iulia Sur, Daniel Samasca, Gabriel Lazea, Cecilia Lazar, Calin |
author_facet | Sur, Lucia M. Gaga, Remus Duca, Emanuela Sur, Genel Lupan, Iulia Sur, Daniel Samasca, Gabriel Lazea, Cecilia Lazar, Calin |
author_sort | Sur, Lucia M. |
collection | PubMed |
description | Juvenile idiopathic arthritis (JIA) represents a significant challenge for pediatricians who intend to diagnose and treat this pathology. The classification criteria for JIA subtypes are rigid and often do not fully satisfy the possibilities of classification in the subtype. The objective of this study was to identify clearer criteria for classifying JIA subtypes. The 2019 expert committee meeting (PRINTO) shows the difficulties of this classification and proposes new research directions for the identification of disease subtypes. Four different chronic disorders are used to define JIA in a concise and easy to follow classification system. However, dates from the literature suggest that at least 10% of cases are still difficult to classify. Possibly in the future, different classifications of JIA based on pathophysiological and genetic criteria would be necessary. |
format | Online Article Text |
id | pubmed-8146979 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-81469792021-05-26 Different Chronic Disorders That Fall within the Term Juvenile Idiopathic Arthritis Sur, Lucia M. Gaga, Remus Duca, Emanuela Sur, Genel Lupan, Iulia Sur, Daniel Samasca, Gabriel Lazea, Cecilia Lazar, Calin Life (Basel) Review Juvenile idiopathic arthritis (JIA) represents a significant challenge for pediatricians who intend to diagnose and treat this pathology. The classification criteria for JIA subtypes are rigid and often do not fully satisfy the possibilities of classification in the subtype. The objective of this study was to identify clearer criteria for classifying JIA subtypes. The 2019 expert committee meeting (PRINTO) shows the difficulties of this classification and proposes new research directions for the identification of disease subtypes. Four different chronic disorders are used to define JIA in a concise and easy to follow classification system. However, dates from the literature suggest that at least 10% of cases are still difficult to classify. Possibly in the future, different classifications of JIA based on pathophysiological and genetic criteria would be necessary. MDPI 2021-04-27 /pmc/articles/PMC8146979/ /pubmed/33925491 http://dx.doi.org/10.3390/life11050398 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Sur, Lucia M. Gaga, Remus Duca, Emanuela Sur, Genel Lupan, Iulia Sur, Daniel Samasca, Gabriel Lazea, Cecilia Lazar, Calin Different Chronic Disorders That Fall within the Term Juvenile Idiopathic Arthritis |
title | Different Chronic Disorders That Fall within the Term Juvenile Idiopathic Arthritis |
title_full | Different Chronic Disorders That Fall within the Term Juvenile Idiopathic Arthritis |
title_fullStr | Different Chronic Disorders That Fall within the Term Juvenile Idiopathic Arthritis |
title_full_unstemmed | Different Chronic Disorders That Fall within the Term Juvenile Idiopathic Arthritis |
title_short | Different Chronic Disorders That Fall within the Term Juvenile Idiopathic Arthritis |
title_sort | different chronic disorders that fall within the term juvenile idiopathic arthritis |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146979/ https://www.ncbi.nlm.nih.gov/pubmed/33925491 http://dx.doi.org/10.3390/life11050398 |
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