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Toward an Understanding of the Structural and Mechanistic Aspects of Protein-Protein Interactions in 2-Oxoacid Dehydrogenase Complexes

The 2-oxoglutarate dehydrogenase complex (OGDHc) is a key enzyme in the tricarboxylic acid (TCA) cycle and represents one of the major regulators of mitochondrial metabolism through NADH and reactive oxygen species levels. The OGDHc impacts cell metabolic and cell signaling pathways through the coup...

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Detalles Bibliográficos
Autores principales: Nemeria, Natalia S., Zhang, Xu, Leandro, Joao, Zhou, Jieyu, Yang, Luying, Houten, Sander M., Jordan, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146983/
https://www.ncbi.nlm.nih.gov/pubmed/33946784
http://dx.doi.org/10.3390/life11050407

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