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Toward an Understanding of the Structural and Mechanistic Aspects of Protein-Protein Interactions in 2-Oxoacid Dehydrogenase Complexes
The 2-oxoglutarate dehydrogenase complex (OGDHc) is a key enzyme in the tricarboxylic acid (TCA) cycle and represents one of the major regulators of mitochondrial metabolism through NADH and reactive oxygen species levels. The OGDHc impacts cell metabolic and cell signaling pathways through the coup...
Autores principales: | Nemeria, Natalia S., Zhang, Xu, Leandro, Joao, Zhou, Jieyu, Yang, Luying, Houten, Sander M., Jordan, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146983/ https://www.ncbi.nlm.nih.gov/pubmed/33946784 http://dx.doi.org/10.3390/life11050407 |
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