Rapamycin Improves Spatial Learning Deficits, Vulnerability to Alcohol Addiction and Altered Expression of the GluN2B Subunit of the NMDA Receptor in Adult Rats Exposed to Ethanol during the Neonatal Period

Ethanol exposure during pregnancy alters the mammalian target of rapamycin (mTOR) signaling pathway in the fetal brain. Hence, in adult rats exposed to ethanol during the neonatal period, we investigated the influence of rapamycin, an mTOR Complex 1 (mTORC1) inhibitor, on deficits in spatial memory...

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Detalles Bibliográficos
Autores principales: Lopatynska-Mazurek, Malgorzata, Antolak, Anna, Grochecki, Pawel, Gibula-Tarlowska, Ewa, Bodzon-Kulakowska, Anna, Listos, Joanna, Kedzierska, Ewa, Suder, Piotr, Silberring, Jerzy, Kotlinska, Jolanta H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147055/
https://www.ncbi.nlm.nih.gov/pubmed/33924998
http://dx.doi.org/10.3390/biom11050650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147055/
https://www.ncbi.nlm.nih.gov/pubmed/33924998
http://dx.doi.org/10.3390/biom11050650

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