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Rapamycin Improves Spatial Learning Deficits, Vulnerability to Alcohol Addiction and Altered Expression of the GluN2B Subunit of the NMDA Receptor in Adult Rats Exposed to Ethanol during the Neonatal Period
Ethanol exposure during pregnancy alters the mammalian target of rapamycin (mTOR) signaling pathway in the fetal brain. Hence, in adult rats exposed to ethanol during the neonatal period, we investigated the influence of rapamycin, an mTOR Complex 1 (mTORC1) inhibitor, on deficits in spatial memory...
Autores principales: | Lopatynska-Mazurek, Malgorzata, Antolak, Anna, Grochecki, Pawel, Gibula-Tarlowska, Ewa, Bodzon-Kulakowska, Anna, Listos, Joanna, Kedzierska, Ewa, Suder, Piotr, Silberring, Jerzy, Kotlinska, Jolanta H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147055/ https://www.ncbi.nlm.nih.gov/pubmed/33924998 http://dx.doi.org/10.3390/biom11050650 |
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