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scDesign2: a transparent simulator that generates high-fidelity single-cell gene expression count data with gene correlations captured
A pressing challenge in single-cell transcriptomics is to benchmark experimental protocols and computational methods. A solution is to use computational simulators, but existing simulators cannot simultaneously achieve three goals: preserving genes, capturing gene correlations, and generating any nu...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147071/ https://www.ncbi.nlm.nih.gov/pubmed/34034771 http://dx.doi.org/10.1186/s13059-021-02367-2 |