Effects of diabetes on the development of radiation pneumonitis

Radiation pneumonia (RP) is a common adverse reaction to radiation therapy in patients with chest tumors. Recent studies have shown that diabetes mellitus (DM), which can cause systemic multisystem damage, specifically targets lungs, and the incidence of RP in patients with a history of diabetes is...

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Autores principales: Dong, Guangtong, Li, Yuxiao, Zhao, Qiyao, Pang, Bing, Qi, Xin, Wei, Junping, Hou, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147083/
https://www.ncbi.nlm.nih.gov/pubmed/34030688
http://dx.doi.org/10.1186/s12931-021-01754-4
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author Dong, Guangtong
Li, Yuxiao
Zhao, Qiyao
Pang, Bing
Qi, Xin
Wei, Junping
Hou, Wei
author_facet Dong, Guangtong
Li, Yuxiao
Zhao, Qiyao
Pang, Bing
Qi, Xin
Wei, Junping
Hou, Wei
author_sort Dong, Guangtong
collection PubMed
description Radiation pneumonia (RP) is a common adverse reaction to radiation therapy in patients with chest tumors. Recent studies have shown that diabetes mellitus (DM), which can cause systemic multisystem damage, specifically targets lungs, and the incidence of RP in patients with a history of diabetes is higher than that in other patients with tumors who have undergone radiotherapy. DM is an important risk factor for RP in tumor patients undergoing RT, and patients with DM should be treated with caution. This article reviews research on the clinical aspects, as well as the mechanism, of the effects of diabetes on RP and suggests future research needed to reduce RP.
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spelling pubmed-81470832021-05-25 Effects of diabetes on the development of radiation pneumonitis Dong, Guangtong Li, Yuxiao Zhao, Qiyao Pang, Bing Qi, Xin Wei, Junping Hou, Wei Respir Res Review Radiation pneumonia (RP) is a common adverse reaction to radiation therapy in patients with chest tumors. Recent studies have shown that diabetes mellitus (DM), which can cause systemic multisystem damage, specifically targets lungs, and the incidence of RP in patients with a history of diabetes is higher than that in other patients with tumors who have undergone radiotherapy. DM is an important risk factor for RP in tumor patients undergoing RT, and patients with DM should be treated with caution. This article reviews research on the clinical aspects, as well as the mechanism, of the effects of diabetes on RP and suggests future research needed to reduce RP. BioMed Central 2021-05-24 2021 /pmc/articles/PMC8147083/ /pubmed/34030688 http://dx.doi.org/10.1186/s12931-021-01754-4 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Dong, Guangtong
Li, Yuxiao
Zhao, Qiyao
Pang, Bing
Qi, Xin
Wei, Junping
Hou, Wei
Effects of diabetes on the development of radiation pneumonitis
title Effects of diabetes on the development of radiation pneumonitis
title_full Effects of diabetes on the development of radiation pneumonitis
title_fullStr Effects of diabetes on the development of radiation pneumonitis
title_full_unstemmed Effects of diabetes on the development of radiation pneumonitis
title_short Effects of diabetes on the development of radiation pneumonitis
title_sort effects of diabetes on the development of radiation pneumonitis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147083/
https://www.ncbi.nlm.nih.gov/pubmed/34030688
http://dx.doi.org/10.1186/s12931-021-01754-4
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