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Endothelial and Vascular Health: A Tale of Honey, H(2)O(2) and Calcium
Intracellular Ca(2+) regulation plays a pivotal role in endothelial biology as well as during endothelial restoration processes. Interest in honey utilization in wound approaches is rising in recent years. In order to evaluate the positive effects of buckwheat honey on endothelial responses, we util...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147193/ https://www.ncbi.nlm.nih.gov/pubmed/33946572 http://dx.doi.org/10.3390/cells10051071 |
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author | Ranzato, Elia Bonsignore, Gregorio Patrone, Mauro Martinotti, Simona |
author_facet | Ranzato, Elia Bonsignore, Gregorio Patrone, Mauro Martinotti, Simona |
author_sort | Ranzato, Elia |
collection | PubMed |
description | Intracellular Ca(2+) regulation plays a pivotal role in endothelial biology as well as during endothelial restoration processes. Interest in honey utilization in wound approaches is rising in recent years. In order to evaluate the positive effects of buckwheat honey on endothelial responses, we utilized an immortalized endothelial cell line to evaluate cellular responses upon honey exposure, with particular interest in Ca(2+) signaling involvement. The results highlight the positive effects of buckwheat honey on endothelial cells’ responses and the central role played by Ca(2+) signaling as an encouraging target for more efficacious clinical treatments. |
format | Online Article Text |
id | pubmed-8147193 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-81471932021-05-26 Endothelial and Vascular Health: A Tale of Honey, H(2)O(2) and Calcium Ranzato, Elia Bonsignore, Gregorio Patrone, Mauro Martinotti, Simona Cells Article Intracellular Ca(2+) regulation plays a pivotal role in endothelial biology as well as during endothelial restoration processes. Interest in honey utilization in wound approaches is rising in recent years. In order to evaluate the positive effects of buckwheat honey on endothelial responses, we utilized an immortalized endothelial cell line to evaluate cellular responses upon honey exposure, with particular interest in Ca(2+) signaling involvement. The results highlight the positive effects of buckwheat honey on endothelial cells’ responses and the central role played by Ca(2+) signaling as an encouraging target for more efficacious clinical treatments. MDPI 2021-04-30 /pmc/articles/PMC8147193/ /pubmed/33946572 http://dx.doi.org/10.3390/cells10051071 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Ranzato, Elia Bonsignore, Gregorio Patrone, Mauro Martinotti, Simona Endothelial and Vascular Health: A Tale of Honey, H(2)O(2) and Calcium |
title | Endothelial and Vascular Health: A Tale of Honey, H(2)O(2) and Calcium |
title_full | Endothelial and Vascular Health: A Tale of Honey, H(2)O(2) and Calcium |
title_fullStr | Endothelial and Vascular Health: A Tale of Honey, H(2)O(2) and Calcium |
title_full_unstemmed | Endothelial and Vascular Health: A Tale of Honey, H(2)O(2) and Calcium |
title_short | Endothelial and Vascular Health: A Tale of Honey, H(2)O(2) and Calcium |
title_sort | endothelial and vascular health: a tale of honey, h(2)o(2) and calcium |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147193/ https://www.ncbi.nlm.nih.gov/pubmed/33946572 http://dx.doi.org/10.3390/cells10051071 |
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