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Endothelial and Vascular Health: A Tale of Honey, H(2)O(2) and Calcium

Intracellular Ca(2+) regulation plays a pivotal role in endothelial biology as well as during endothelial restoration processes. Interest in honey utilization in wound approaches is rising in recent years. In order to evaluate the positive effects of buckwheat honey on endothelial responses, we util...

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Detalles Bibliográficos
Autores principales: Ranzato, Elia, Bonsignore, Gregorio, Patrone, Mauro, Martinotti, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147193/
https://www.ncbi.nlm.nih.gov/pubmed/33946572
http://dx.doi.org/10.3390/cells10051071
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author Ranzato, Elia
Bonsignore, Gregorio
Patrone, Mauro
Martinotti, Simona
author_facet Ranzato, Elia
Bonsignore, Gregorio
Patrone, Mauro
Martinotti, Simona
author_sort Ranzato, Elia
collection PubMed
description Intracellular Ca(2+) regulation plays a pivotal role in endothelial biology as well as during endothelial restoration processes. Interest in honey utilization in wound approaches is rising in recent years. In order to evaluate the positive effects of buckwheat honey on endothelial responses, we utilized an immortalized endothelial cell line to evaluate cellular responses upon honey exposure, with particular interest in Ca(2+) signaling involvement. The results highlight the positive effects of buckwheat honey on endothelial cells’ responses and the central role played by Ca(2+) signaling as an encouraging target for more efficacious clinical treatments.
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spelling pubmed-81471932021-05-26 Endothelial and Vascular Health: A Tale of Honey, H(2)O(2) and Calcium Ranzato, Elia Bonsignore, Gregorio Patrone, Mauro Martinotti, Simona Cells Article Intracellular Ca(2+) regulation plays a pivotal role in endothelial biology as well as during endothelial restoration processes. Interest in honey utilization in wound approaches is rising in recent years. In order to evaluate the positive effects of buckwheat honey on endothelial responses, we utilized an immortalized endothelial cell line to evaluate cellular responses upon honey exposure, with particular interest in Ca(2+) signaling involvement. The results highlight the positive effects of buckwheat honey on endothelial cells’ responses and the central role played by Ca(2+) signaling as an encouraging target for more efficacious clinical treatments. MDPI 2021-04-30 /pmc/articles/PMC8147193/ /pubmed/33946572 http://dx.doi.org/10.3390/cells10051071 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ranzato, Elia
Bonsignore, Gregorio
Patrone, Mauro
Martinotti, Simona
Endothelial and Vascular Health: A Tale of Honey, H(2)O(2) and Calcium
title Endothelial and Vascular Health: A Tale of Honey, H(2)O(2) and Calcium
title_full Endothelial and Vascular Health: A Tale of Honey, H(2)O(2) and Calcium
title_fullStr Endothelial and Vascular Health: A Tale of Honey, H(2)O(2) and Calcium
title_full_unstemmed Endothelial and Vascular Health: A Tale of Honey, H(2)O(2) and Calcium
title_short Endothelial and Vascular Health: A Tale of Honey, H(2)O(2) and Calcium
title_sort endothelial and vascular health: a tale of honey, h(2)o(2) and calcium
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147193/
https://www.ncbi.nlm.nih.gov/pubmed/33946572
http://dx.doi.org/10.3390/cells10051071
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