Ion-Complex Microcrystal Formulation Provides Sustained Delivery of a Multimodal Kinase Inhibitor from the Subconjunctival Space for Protection of Retinal Ganglion Cells

Glaucoma is the leading cause of irreversible blindness worldwide. Elevated intraocular pressure (IOP) is one of the major risk factors for glaucoma onset and progression, and available pharmaceutical interventions are exclusively targeted at IOP lowering. However, degeneration of retinal ganglion c...

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Detalles Bibliográficos
Autores principales: Hsueh, Henry T., Kim, Yoo-Chun, Pitha, Ian, Shin, Matthew D., Berlinicke, Cynthia A., Chou, Renee Ti, Kimball, Elizabeth, Schaub, Julie, Quillen, Sarah, Leo, Kirby T., Han, Hyounkoo, Xiao, Amy, Kim, Youngwook, Appell, Matthew, Rai, Usha, Kwon, HyeYoung, Kolodziejski, Patricia, Ogunnaike, Laolu, Anders, Nicole M., Hemingway, Avelina, Jefferys, Joan L., Date, Abhijit A., Eberhart, Charles, Johnson, Thomas V., Quigley, Harry A., Zack, Donald J., Hanes, Justin, Ensign, Laura M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147274/
https://www.ncbi.nlm.nih.gov/pubmed/34062883
http://dx.doi.org/10.3390/pharmaceutics13050647

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