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Overexpression of Lipocalin-2 Inhibits Proliferation and Invasiveness of Human Glioblastoma Multiforme Cells by Activating ERK Targeting Cathepsin D Expression

SIMPLE SUMMARY: Lipocalin-2 (LCN2) exhibits pro- and anti-carcinogenic effects in several cancers, but its role in the progression of glioblastoma multiforme (GBM) remains poorly understood. We observed that the overexpression of LCN2 inhibits GBM cell proliferation and invasion via activation of ER...

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Detalles Bibliográficos
Autores principales: Hsieh, Yi-Hsien, Tsai, Jen-Pi, Yu, Chen-Lin, Lee, Chu-Che, Hsu, Jen-Chieh, Chen, Jin-Cherng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147321/
https://www.ncbi.nlm.nih.gov/pubmed/34062746
http://dx.doi.org/10.3390/biology10050390