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Overexpression of Lipocalin-2 Inhibits Proliferation and Invasiveness of Human Glioblastoma Multiforme Cells by Activating ERK Targeting Cathepsin D Expression
SIMPLE SUMMARY: Lipocalin-2 (LCN2) exhibits pro- and anti-carcinogenic effects in several cancers, but its role in the progression of glioblastoma multiforme (GBM) remains poorly understood. We observed that the overexpression of LCN2 inhibits GBM cell proliferation and invasion via activation of ER...
Autores principales: | Hsieh, Yi-Hsien, Tsai, Jen-Pi, Yu, Chen-Lin, Lee, Chu-Che, Hsu, Jen-Chieh, Chen, Jin-Cherng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147321/ https://www.ncbi.nlm.nih.gov/pubmed/34062746 http://dx.doi.org/10.3390/biology10050390 |
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