Cargando…

Zika virus induces neuronal and vascular degeneration in developing mouse retina

Zika virus (ZIKV), a mosquito-borne flavivirus, can cause severe eye disease and even blindness in newborns. However, ZIKV-induced retinal lesions have not been studied in a comprehensive way, mechanisms of ZIKV-induced retinal abnormalities are unknown, and no therapeutic intervention is available...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Yi, Shi, Shuizhen, Xia, Fan, Shan, Chao, Ha, Yonju, Zou, Jing, Adam, Awadalkareem, Zhang, Ming, Wang, Tian, Liu, Hua, Shi, Pei-Yong, Zhang, Wenbo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147371/ https://www.ncbi.nlm.nih.gov/pubmed/34034828 http://dx.doi.org/10.1186/s40478-021-01195-6

Ejemplares similares

Early alterations of neurovascular unit in the retina in mouse models of tauopathy
por: Xia, Fan, et al.
Publicado: (2021)

Neuronal Epac1 mediates retinal neurodegeneration in mouse models of ocular hypertension
por: Liu, Wei, et al.
Publicado: (2020)

Peli1 signaling blockade attenuates congenital zika syndrome
por: Luo, Huanle, et al.
Publicado: (2020)

Curcumin Inhibits Neuronal and Vascular Degeneration in Retina after Ischemia and Reperfusion Injury
por: Wang, Leilei, et al.
Publicado: (2011)

Rational Development of Live-Attenuated Zika Virus Vaccines
por: Adam, Awadalkareem, et al.
Publicado: (2023)

Epidemiology and Laboratory Diagnostics of Dengue, Yellow Fever, Zika, and Chikungunya Virus Infections in Africa
por: Adam, Awadalkareem, et al.
Publicado: (2021)

Upregulation of HLA‐E by dengue and not Zika viruses
por: Drews, Elena, et al.
Publicado: (2018)

Genetic and biochemical characterizations of Zika virus NS2A protein
por: Zhang, Xianwen, et al.
Publicado: (2019)

Sortilin Inhibition Protects Neurons From Degeneration in the Diabetic Retina
por: Jakobsen, Thomas Stax, et al.
Publicado: (2023)

PERK Inhibition Suppresses Neovascularization and Protects Neurons During Ischemia-Induced Retinopathy
por: Shi, Shuizhen, et al.
Publicado: (2023)

Neonatal Hyperglycemia Inhibits Angiogenesis and Induces Inflammation and Neuronal Degeneration in the Retina
por: Kermorvant-Duchemin, Elsa, et al.
Publicado: (2013)

An attenuated Zika virus NS4B protein mutant is a potent inducer of antiviral immune responses
por: Li, Guangyu, et al.
Publicado: (2019)

Zika Virus Replicons for Drug Discovery
por: Xie, Xuping, et al.
Publicado: (2016)

Degeneration of the mouse retina upon dysregulated activity of serum response factor
por: Sandström, Jenny, et al.
Publicado: (2011)

Synaptic remodeling generates synchronous oscillations in the degenerated outer mouse retina
por: Haq, Wadood, et al.
Publicado: (2014)

Nestin Expression in the Adult Mouse Retina with Pharmaceutically Induced Retinal Degeneration
por: Moon, Chan Hee, et al.
Publicado: (2017)

Editorial: Neuronal Development and Degeneration
por: Fort, Patrice E., et al.
Publicado: (2019)

Oxidative Stress Induces Endothelial Cell Senescence via Downregulation of Sirt6
por: Liu, Rong, et al.
Publicado: (2014)

Longitudinal characterization of retinal vasculature alterations with optical coherence tomography angiography in a mouse model of tauopathy
por: Buscho, Seth, et al.
Publicado: (2022)

AAV2-mediated GRP78 Transfer Alleviates Retinal Neuronal Injury by Downregulating ER Stress and Tau Oligomer Formation
por: Ha, Yonju, et al.
Publicado: (2018)

A genetically stable Zika virus vaccine candidate protects mice against virus infection and vertical transmission
por: Adam, Awadalkareem, et al.
Publicado: (2021)

Origins of spontaneous activity in the degenerating retina
por: Trenholm, Stuart, et al.
Publicado: (2015)

Sphingolipids as Emerging Mediators in Retina Degeneration
por: Simón, M. Victoria, et al.
Publicado: (2019)

Mutations in spliceosomal proteins and retina degeneration
por: Růžičková, Šárka, et al.
Publicado: (2016)

Analyzing neural degeneration of the retina with connectomics
por: Zucker, Charles L., et al.
Publicado: (2021)

Ciliary neurotrophic factor-mediated neuroprotection involves enhanced glycolysis and anabolism in degenerating mouse retinas
por: Do Rhee, Kun, et al.
Publicado: (2022)

A platform of assays for the discovery of anti-Zika small-molecules with activity in a 3D-bioprinted outer-blood-retina model
por: Dorjsuren, Dorjbal, et al.
Publicado: (2022)

Destructive Changes in the Neuronal Structure of the FVB/N Mouse Retina
por: Yang, Jinnan, et al.
Publicado: (2015)

Response of Mouse Visual Cortical Neurons to Electric Stimulation of the Retina
por: Ryu, Sang Baek, et al.
Publicado: (2019)

Oxidative Stress, Vascular Endothelium, and the Pathology of Neurodegeneration in Retina
por: Shi, Xin, et al.
Publicado: (2022)

Adulthood Sequelae of Congenital Zika Virus Infection in Mice
por: Zou, Jing, et al.
Publicado: (2017)

The temporal topography of the N-Methyl- N-nitrosourea induced photoreceptor degeneration in mouse retina
por: Tao, Ye, et al.
Publicado: (2015)

Hypoxic–ischemic injury causes functional and structural neurovascular degeneration in the juvenile mouse retina
por: Zaitoun, Ismail S., et al.
Publicado: (2021)

Competition for endothelial cell polarity drives vascular morphogenesis in the mouse retina
por: Barbacena, Pedro, et al.
Publicado: (2022)

Zika Virus NS2A-Mediated Virion Assembly
por: Zhang, Xianwen, et al.
Publicado: (2019)

Vascular and Neuronal Protection in the Developing Retina: Potential Therapeutic Targets for Retinopathy of Prematurity
por: Tsang, Jessica K. W., et al.
Publicado: (2019)

Epac1 and Glycyrrhizin Both Inhibit HMGB1 Levels to Reduce Diabetes-Induced Neuronal and Vascular Damage in the Mouse Retina
por: Liu, Li, et al.
Publicado: (2019)

Multiple Independent Oscillatory Networks in the Degenerating Retina
por: Euler, Thomas, et al.
Publicado: (2015)

An activated unfolded protein response promotes retinal degeneration and triggers an inflammatory response in the mouse retina
por: Rana, T, et al.
Publicado: (2014)

Watching synchronous mitochondrial respiration in the retina and its instability in a mouse model of macular degeneration
por: Kaynezhad, Pardis, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_v036r5lng3cfd8kn37asct0r5t