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ICG-001, an Inhibitor of the β-Catenin and cAMP Response Element-Binding Protein Dependent Gene Transcription, Decreases Proliferation but Enhances Migration of Osteosarcoma Cells

High-grade osteosarcomas are the most frequent malignant bone tumors in the pediatric population, with 150 patients diagnosed every year in France. Osteosarcomas are associated with low survival rates for high risk patients (metastatic and relapsed diseases). Knowing that the canonical Wnt signaling...

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Detalles Bibliográficos
Autores principales: Danieau, Geoffroy, Morice, Sarah, Renault, Sarah, Brion, Régis, Biteau, Kevin, Amiaud, Jérôme, Cadé, Marie, Heymann, Dominique, Lézot, Frédéric, Verrecchia, Franck, Rédini, Françoise, Brounais-Le Royer, Bénédicte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147379/
https://www.ncbi.nlm.nih.gov/pubmed/34062831
http://dx.doi.org/10.3390/ph14050421

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