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ALK7 Acts as a Positive Regulator of Macrophage Activation through Down-Regulation of PPARγ Expression

Aim: Activin receptor-like kinase 7 (ALK7) acts as a key receptor for TGF-β family members, which play important roles in regulating cardiovascular activity. However, ALK7's potential role, and underlying mechanism, in the macrophage activation involved in atherogenesis remain unexplored. Metho...

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Detalles Bibliográficos
Autores principales: Cheng, Wen-Lin, Zhang, Quan, Cao, Jian-Lei, Chen, Xi-Lu, Li, Wenyan, Zhang, Lin, Chao, Sheng-ping, Zhao, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Atherosclerosis Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147563/
https://www.ncbi.nlm.nih.gov/pubmed/32641645
http://dx.doi.org/10.5551/jat.54445