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The Evolution of Antisense Oligonucleotide Chemistry—A Personal Journey
Over the last four decades, tremendous progress has been made in use of synthetic oligonucleotides as therapeutics. This has been possible largely by introducing chemical modifications to provide drug like properties to oligonucleotides. In this article I have summarized twists and turns on use of c...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147625/ https://www.ncbi.nlm.nih.gov/pubmed/34063675 http://dx.doi.org/10.3390/biomedicines9050503 |