Stability of centrosome numbers in poly(ADP-ribose) polymerase-1- and poly(ADP-ribose) glycohydrolase-deficient mouse ES cells

Poly(ADP-ribose) polymerase-1 (Parp-1) localizes mainly in the nucleus and functions in DNA repair, genome stability and cell death regulation. Meanwhile, it also localizes in centrosomes and is involved in the regulation of centrosome duplication. An abnormal increase in centrosome numbers is frequ...

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Detalles Bibliográficos
Autores principales: Ogino, Hideki, Gunji, Akemi, Kamada, Nobuo, Nakagama, Hitoshi, Sugimura, Takashi, Masutani, Mitsuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Academy 2004
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147680/

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