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Animal Fat Intake Is Associated with Albuminuria in Patients with Non-Alcoholic Fatty Liver Disease and Metabolic Syndrome

Non-alcoholic fatty liver disease (NAFLD) and metabolic syndrome (MetS) are associated with chronic kidney disease (CKD). Diet could play a predisposing role in the development of increased albuminuria in patients with NAFLD and MetS; however, published evidence is still limited. The aim of this cro...

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Autores principales: Abbate, Manuela, Mascaró, Catalina M., Montemayor, Sofía, Barbería-Latasa, María, Casares, Miguel, Gómez, Cristina, Ugarriza, Lucia, Tejada, Silvia, Abete, Itziar, Zulet, María Ángeles, Sureda, Antoni, Martínez, J. Alfredo, Tur, Josep A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147815/
https://www.ncbi.nlm.nih.gov/pubmed/34064372
http://dx.doi.org/10.3390/nu13051548
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author Abbate, Manuela
Mascaró, Catalina M.
Montemayor, Sofía
Barbería-Latasa, María
Casares, Miguel
Gómez, Cristina
Ugarriza, Lucia
Tejada, Silvia
Abete, Itziar
Zulet, María Ángeles
Sureda, Antoni
Martínez, J. Alfredo
Tur, Josep A.
author_facet Abbate, Manuela
Mascaró, Catalina M.
Montemayor, Sofía
Barbería-Latasa, María
Casares, Miguel
Gómez, Cristina
Ugarriza, Lucia
Tejada, Silvia
Abete, Itziar
Zulet, María Ángeles
Sureda, Antoni
Martínez, J. Alfredo
Tur, Josep A.
author_sort Abbate, Manuela
collection PubMed
description Non-alcoholic fatty liver disease (NAFLD) and metabolic syndrome (MetS) are associated with chronic kidney disease (CKD). Diet could play a predisposing role in the development of increased albuminuria in patients with NAFLD and MetS; however, published evidence is still limited. The aim of this cross-sectional analysis was to assess whether dietary fats are associated with changes in urinary albumin-to-creatinine ratio (UACR) in 146 patients aged 40–60-years with NAFLD and MetS. Dietary data were collected by food frequency questionnaire; UACR was measured in a single first morning void. Sources and types of dietary fats used in the analysis were total fat, fats from animal and vegetable sources, saturated, monounsaturated, polyunsaturated, and trans fats. One-way analysis of variance was performed to assess differences in dietary fats intakes across stages of UACR. The association between dietary fats and UACR was assessed by Pearson’s correlation coefficient and multivariable linear regression. Patients with increased UACR showed a worse cardiometabolic profile and higher intakes of animal fat, as compared to patients with normal levels of albuminuria. Animal fat intake was associated with mean UACR, independent of potential covariates.
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spelling pubmed-81478152021-05-26 Animal Fat Intake Is Associated with Albuminuria in Patients with Non-Alcoholic Fatty Liver Disease and Metabolic Syndrome Abbate, Manuela Mascaró, Catalina M. Montemayor, Sofía Barbería-Latasa, María Casares, Miguel Gómez, Cristina Ugarriza, Lucia Tejada, Silvia Abete, Itziar Zulet, María Ángeles Sureda, Antoni Martínez, J. Alfredo Tur, Josep A. Nutrients Article Non-alcoholic fatty liver disease (NAFLD) and metabolic syndrome (MetS) are associated with chronic kidney disease (CKD). Diet could play a predisposing role in the development of increased albuminuria in patients with NAFLD and MetS; however, published evidence is still limited. The aim of this cross-sectional analysis was to assess whether dietary fats are associated with changes in urinary albumin-to-creatinine ratio (UACR) in 146 patients aged 40–60-years with NAFLD and MetS. Dietary data were collected by food frequency questionnaire; UACR was measured in a single first morning void. Sources and types of dietary fats used in the analysis were total fat, fats from animal and vegetable sources, saturated, monounsaturated, polyunsaturated, and trans fats. One-way analysis of variance was performed to assess differences in dietary fats intakes across stages of UACR. The association between dietary fats and UACR was assessed by Pearson’s correlation coefficient and multivariable linear regression. Patients with increased UACR showed a worse cardiometabolic profile and higher intakes of animal fat, as compared to patients with normal levels of albuminuria. Animal fat intake was associated with mean UACR, independent of potential covariates. MDPI 2021-05-04 /pmc/articles/PMC8147815/ /pubmed/34064372 http://dx.doi.org/10.3390/nu13051548 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Abbate, Manuela
Mascaró, Catalina M.
Montemayor, Sofía
Barbería-Latasa, María
Casares, Miguel
Gómez, Cristina
Ugarriza, Lucia
Tejada, Silvia
Abete, Itziar
Zulet, María Ángeles
Sureda, Antoni
Martínez, J. Alfredo
Tur, Josep A.
Animal Fat Intake Is Associated with Albuminuria in Patients with Non-Alcoholic Fatty Liver Disease and Metabolic Syndrome
title Animal Fat Intake Is Associated with Albuminuria in Patients with Non-Alcoholic Fatty Liver Disease and Metabolic Syndrome
title_full Animal Fat Intake Is Associated with Albuminuria in Patients with Non-Alcoholic Fatty Liver Disease and Metabolic Syndrome
title_fullStr Animal Fat Intake Is Associated with Albuminuria in Patients with Non-Alcoholic Fatty Liver Disease and Metabolic Syndrome
title_full_unstemmed Animal Fat Intake Is Associated with Albuminuria in Patients with Non-Alcoholic Fatty Liver Disease and Metabolic Syndrome
title_short Animal Fat Intake Is Associated with Albuminuria in Patients with Non-Alcoholic Fatty Liver Disease and Metabolic Syndrome
title_sort animal fat intake is associated with albuminuria in patients with non-alcoholic fatty liver disease and metabolic syndrome
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147815/
https://www.ncbi.nlm.nih.gov/pubmed/34064372
http://dx.doi.org/10.3390/nu13051548
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