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In Situ Maturated Early-Stage Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Improve Cardiac Function by Enhancing Segmental Contraction in Infarcted Rats

The scant ability of cardiomyocytes to proliferate makes heart regeneration one of the biggest challenges of science. Current therapies do not contemplate heart re-muscularization. In this scenario, stem cell-based approaches have been proposed to overcome this lack of regeneration. We hypothesize t...

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Detalles Bibliográficos
Autores principales: Biagi, Diogo, Fantozzi, Evelyn Thais, Campos-Oliveira, Julliana Carvalho, Naghetini, Marcus Vinicius, Ribeiro, Antonio Fernando, Rodrigues, Sirlene, Ogusuku, Isabella, Vanderlinde, Rubia, Christie, Michelle Lopes Araújo, Mello, Debora Bastos, de Carvalho, Antonio Carlos Campos, Valadares, Marcos, Cruvinel, Estela, Dariolli, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147857/
https://www.ncbi.nlm.nih.gov/pubmed/34064343
http://dx.doi.org/10.3390/jpm11050374

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