Cargando…
A Rare Case of Tularemia Complicated by Rhabdomyolysis with a Successful Outcome
We present a case of tularemia complicated by rhabdomyolysis in a 43-year-old male who presented with fever, swelling, and pain of the right groin and a history of a week-old tick bite. Empirical parenteral amoxicillin/clavulanic acid treatment was initiated. Suspecting tularemia, parenteral gentamy...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147915/ https://www.ncbi.nlm.nih.gov/pubmed/34062973 http://dx.doi.org/10.3390/medicina57050449 |
_version_ | 1783697733828214784 |
---|---|
author | Kubiliute, Ieva Zablockiene, Birute Paulauskiene, Rasute Navickas, Giedrius Jancoriene, Ligita |
author_facet | Kubiliute, Ieva Zablockiene, Birute Paulauskiene, Rasute Navickas, Giedrius Jancoriene, Ligita |
author_sort | Kubiliute, Ieva |
collection | PubMed |
description | We present a case of tularemia complicated by rhabdomyolysis in a 43-year-old male who presented with fever, swelling, and pain of the right groin and a history of a week-old tick bite. Empirical parenteral amoxicillin/clavulanic acid treatment was initiated. Suspecting tularemia, parenteral gentamycin was added. Later, the patient started to complain of muscle pain, weakness, and difficulties in breathing and walking. Heightened levels of creatine kinase and myoglobin concentration (42,670 IU/L and >12,000 μg/L, respectively) were found. Due to rhabdomyolysis, large amounts of intravenous fluid therapy were initiated to prevent kidney damage, continuing intravenous antibiotic therapy. Francisella tularensis IgG in serum was found to be positive only on the sixteenth day of hospitalization. Upon discharge, the laboratory analyses returned to normal levels, and the patient was in good condition. The successful outcome could be associated with the early appropriate therapy of tularemia and its rare complication of rhabdomyolysis. |
format | Online Article Text |
id | pubmed-8147915 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-81479152021-05-26 A Rare Case of Tularemia Complicated by Rhabdomyolysis with a Successful Outcome Kubiliute, Ieva Zablockiene, Birute Paulauskiene, Rasute Navickas, Giedrius Jancoriene, Ligita Medicina (Kaunas) Case Report We present a case of tularemia complicated by rhabdomyolysis in a 43-year-old male who presented with fever, swelling, and pain of the right groin and a history of a week-old tick bite. Empirical parenteral amoxicillin/clavulanic acid treatment was initiated. Suspecting tularemia, parenteral gentamycin was added. Later, the patient started to complain of muscle pain, weakness, and difficulties in breathing and walking. Heightened levels of creatine kinase and myoglobin concentration (42,670 IU/L and >12,000 μg/L, respectively) were found. Due to rhabdomyolysis, large amounts of intravenous fluid therapy were initiated to prevent kidney damage, continuing intravenous antibiotic therapy. Francisella tularensis IgG in serum was found to be positive only on the sixteenth day of hospitalization. Upon discharge, the laboratory analyses returned to normal levels, and the patient was in good condition. The successful outcome could be associated with the early appropriate therapy of tularemia and its rare complication of rhabdomyolysis. MDPI 2021-05-05 /pmc/articles/PMC8147915/ /pubmed/34062973 http://dx.doi.org/10.3390/medicina57050449 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Kubiliute, Ieva Zablockiene, Birute Paulauskiene, Rasute Navickas, Giedrius Jancoriene, Ligita A Rare Case of Tularemia Complicated by Rhabdomyolysis with a Successful Outcome |
title | A Rare Case of Tularemia Complicated by Rhabdomyolysis with a Successful Outcome |
title_full | A Rare Case of Tularemia Complicated by Rhabdomyolysis with a Successful Outcome |
title_fullStr | A Rare Case of Tularemia Complicated by Rhabdomyolysis with a Successful Outcome |
title_full_unstemmed | A Rare Case of Tularemia Complicated by Rhabdomyolysis with a Successful Outcome |
title_short | A Rare Case of Tularemia Complicated by Rhabdomyolysis with a Successful Outcome |
title_sort | rare case of tularemia complicated by rhabdomyolysis with a successful outcome |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147915/ https://www.ncbi.nlm.nih.gov/pubmed/34062973 http://dx.doi.org/10.3390/medicina57050449 |
work_keys_str_mv | AT kubiliuteieva ararecaseoftularemiacomplicatedbyrhabdomyolysiswithasuccessfuloutcome AT zablockienebirute ararecaseoftularemiacomplicatedbyrhabdomyolysiswithasuccessfuloutcome AT paulauskienerasute ararecaseoftularemiacomplicatedbyrhabdomyolysiswithasuccessfuloutcome AT navickasgiedrius ararecaseoftularemiacomplicatedbyrhabdomyolysiswithasuccessfuloutcome AT jancorieneligita ararecaseoftularemiacomplicatedbyrhabdomyolysiswithasuccessfuloutcome AT kubiliuteieva rarecaseoftularemiacomplicatedbyrhabdomyolysiswithasuccessfuloutcome AT zablockienebirute rarecaseoftularemiacomplicatedbyrhabdomyolysiswithasuccessfuloutcome AT paulauskienerasute rarecaseoftularemiacomplicatedbyrhabdomyolysiswithasuccessfuloutcome AT navickasgiedrius rarecaseoftularemiacomplicatedbyrhabdomyolysiswithasuccessfuloutcome AT jancorieneligita rarecaseoftularemiacomplicatedbyrhabdomyolysiswithasuccessfuloutcome |