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Partitioning and Spatial Distribution of Drugs in Ocular Surface Tissues

Ocular drug absorption after eye drop instillation has been widely studied, but partitioning phenomena and spatial drug distribution are poorly understood. We investigated partitioning of seven beta-blocking drugs in corneal epithelium, corneal stroma, including endothelium and conjunctiva, using is...

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Detalles Bibliográficos
Autores principales:	Balla, Anusha, Auriola, Seppo, Grey, Angus C., Demarais, Nicholas J., Valtari, Annika, Heikkinen, Emma M., Toropainen, Elisa, Urtti, Arto, Vellonen, Kati-Sisko, Ruponen, Marika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147976/ https://www.ncbi.nlm.nih.gov/pubmed/34064499 http://dx.doi.org/10.3390/pharmaceutics13050658

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