MPRAdecoder: Processing of the Raw MPRA Data With a priori Unknown Sequences of the Region of Interest and Associated Barcodes

Massively parallel reporter assays (MPRAs) enable high-throughput functional evaluation of numerous DNA regulatory elements and/or their mutant variants. The assays are based on the construction of reporter plasmid libraries containing two variable parts, a region of interest (ROI) and a barcode (BC...

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Detalles Bibliográficos
Autores principales: Letiagina, Anna E., Omelina, Evgeniya S., Ivankin, Anton V., Pindyurin, Alexey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148044/
https://www.ncbi.nlm.nih.gov/pubmed/34046055
http://dx.doi.org/10.3389/fgene.2021.618189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148044/
https://www.ncbi.nlm.nih.gov/pubmed/34046055
http://dx.doi.org/10.3389/fgene.2021.618189

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