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Targeting BMI-1-mediated epithelial–mesenchymal transition to inhibit colorectal cancer liver metastasis

Liver is the most common metastatic site for colorectal cancer (CRC), there is no satisfied approach to treat CRC liver metastasis (CRCLM). Here, we investigated the role of a polycomb protein BMI-1 in CRCLM. Immunohistochemical analysis showed that BMI-1 expression in liver metastases was upregulat...

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Detalles Bibliográficos
Autores principales:	Xu, Zhiyao, Zhou, Zhuha, Zhang, Jing, Xuan, Feichao, Fan, Mengjing, Zhou, Difan, Liuyang, Zhenyu, Ma, Ximei, Hong, Yiyang, Wang, Yihong, Sharma, Sherven, Dong, Qinghua, Wang, Guanyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148062/ https://www.ncbi.nlm.nih.gov/pubmed/34094833 http://dx.doi.org/10.1016/j.apsb.2020.11.018

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