Cargando…

BCG Cell Wall Skeleton As a Vaccine Adjuvant Protects Both Infant and Old-Aged Mice from Influenza Virus Infection

Bacillus Calmette-Guerin (BCG) and the cell wall skeleton (CWS) derived from BCG are known to enhance nonspecific immune activation and anti-cancer immunity; however, their roles as a vaccine adjuvant are largely unknown. Here, we report that BCG-CWS acts as a strong immune adjuvant by promoting the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Ki-Hye, Lee, Young-Tae, Park, Yoonsuh, Ko, Eun-Ju, Jung, Yu-Jin, Kim, Yu-Jin, Jo, Eun-Kyeong, Kang, Sang-Moo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148143/ https://www.ncbi.nlm.nih.gov/pubmed/34063125 http://dx.doi.org/10.3390/biomedicines9050516

Ejemplares similares

Distinct Effects of Monophosphoryl Lipid A, Oligodeoxynucleotide CpG, and Combination Adjuvants on Modulating Innate and Adaptive Immune Responses to Influenza Vaccination
por: Ko, Eun-Ju, et al.
Publicado: (2017)

Cell wall skeleton of Mycobacterium bovis BCG enhances the vaccine potential of antigen 85B against tuberculosis by inducing Th1 and Th17 responses
por: Back, Yong Woo, et al.
Publicado: (2019)

Natural Killer and CD8 T Cells Contribute to Protection by Formalin Inactivated Respiratory Syncytial Virus Vaccination under a CD4-Deficient Condition
por: Ko, Eun-Ju, et al.
Publicado: (2020)

Immune adjuvant therapy using Bacillus Calmette–Guérin cell wall skeleton (BCG-CWS) in advanced malignancies: A phase 1 study of safety and immunogenicity assessments
por: Nishida, Sumiyuki, et al.
Publicado: (2019)

Enhanced Intracellular Delivery of BCG Cell Wall Skeleton into Bladder Cancer Cells Using Liposomes Functionalized with Folic Acid and Pep-1 Peptide
por: Yoon, Ho Yub, et al.
Publicado: (2019)

A retrospective study of immunotherapy using the cell wall skeleton of Mycobacterium bovis Bacillus Calmette-Guérin (BCG-CWS) for cervical cancer
por: Shibata, Takeo, et al.
Publicado: (2022)

Cross-Protective Efficacy of Influenza Virus M2e Containing Virus-Like Particles Is Superior to Hemagglutinin Vaccines and Variable Depending on the Genetic Backgrounds of Mice
por: Kim, Yu-Jin, et al.
Publicado: (2017)

A Unique Case of Erdheim-Chester Disease with Axial Skeleton, Lymph Node, and Bone Marrow Involvement
por: Lim, Jin, et al.
Publicado: (2016)

The Adjuvant Activity of BCG Cell Wall Cytoskeleton on a Dengue Virus-2 Subunit Vaccine
por: Jearanaiwitayakul, Tuksin, et al.
Publicado: (2023)

Effective adjuvantation of nanograms of influenza vaccine and induction of cross-protective immunity by physical radiofrequency adjuvant
por: Li, Zhuofan, et al.
Publicado: (2022)

Chest wall granuloma associated with BCG vaccination presenting as hot abscess in an immunocompetent infant
por: Lee, Hyun Seung, et al.
Publicado: (2015)

New vaccines against influenza virus
por: Lee, Young-Tae, et al.
Publicado: (2014)

Intranasal vaccination with M2e5x virus-like particles induces humoral and cellular immune responses conferring cross-protection against heterosubtypic influenza viruses
por: Lee, Young-Tae, et al.
Publicado: (2018)

Assessment of mOMV adjuvant efficacy in the pathogenic H1N1 influenza virus vaccine
por: Lee, Byeong-Jae, et al.
Publicado: (2014)

Evaluation of Waning Immunity at 6 Months after Both Trivalent and Quadrivalent Influenza Vaccination in Korean Children Aged 6–35 Months
por: Lee, Jee Hyun, et al.
Publicado: (2019)

Adjuvant effects of combination monophosphoryl lipid A and poly I:C on antigen-specific immune responses and protective efficacy of influenza vaccines
por: Le, Chau Thuy Tien, et al.
Publicado: (2023)

Harris lines observed in human skeletons of Joseon Dynasty, Korea
por: Beom, Jaewon, et al.
Publicado: (2014)

Immunomodulatory Activity of Red Ginseng against Influenza A Virus Infection
por: Lee, Jong Seok, et al.
Publicado: (2014)

Adjuvant Effects of a New Saponin Analog VSA-1 on Enhancing Homologous and Heterosubtypic Protection by Influenza Virus Vaccination
por: Bhatnagar, Noopur, et al.
Publicado: (2022)

Effective inactivated influenza vaccine for the elderly using a single-stranded RNA-based adjuvant
por: Bang, Yoo-Jin, et al.
Publicado: (2021)

Hemagglutinin virus-like particles incorporated with membrane-bound cytokine adjuvants provide protection against homologous and heterologous influenza virus challenge in aged mice
por: Park, Bo Ryoung, et al.
Publicado: (2023)

An M. Boms BCG cell wall glicopeptid — EIA for antituberculosis antibodies detection
por: Romanova, R.Yu., et al.
Publicado: (1994)

Virus-Like Particles Are a Superior Platform for Presenting M2e Epitopes to Prime Humoral and Cellular Immunity against Influenza Virus
por: Kim, Ki-Hye, et al.
Publicado: (2018)

The impact of an educational intervention on parents' decisions to vaccinate their <60-month-old children against influenza
por: Choi, Aery, et al.
Publicado: (2017)

Management of Eosinophilic Granuloma Occurring in the Appendicular Skeleton in Children
por: Han, Ilkyu, et al.
Publicado: (2009)

The Association of BCG Vaccination with Atopy and Asthma in Adults
por: Park, Sung Soo, et al.
Publicado: (2015)

Performance of the tuberculin skin test and interferon-γ release assay for detection of tuberculosis infection in immunocompromised patients in a BCG-vaccinated population
por: Kim, Eun Young, et al.
Publicado: (2009)

Recombinant BCG: Innovations on an Old Vaccine. Scope of BCG Strains and Strategies to Improve Long-Lasting Memory
por: da Costa, Adeliane Castro, et al.
Publicado: (2014)

Itaconate, Arginine, and Gamma-Aminobutyric Acid: A Host Metabolite Triad Protective Against Mycobacterial Infection
por: Kim, Jin Kyung, et al.
Publicado: (2022)

Educational Case: Giant Cell Tumor of the Bone in Both the Axial and Appendicular Skeleton
por: Shaia, Jacqueline K., et al.
Publicado: (2021)

Effect of fibrin glue as an adjuvant to hang-back surgery
por: Park, Jihyun, et al.
Publicado: (2012)

Antiviral Activity of Fermented Ginseng Extracts against a Broad Range of Influenza Viruses
por: Wang, Ye, et al.
Publicado: (2018)

The efficacy of a 2,4-diaminoquinazoline compound as an intranasal vaccine adjuvant to protect against influenza A virus infection in vivo
por: Noh, Kyungseob, et al.
Publicado: (2022)

Comparison of Filtered Back Projection, Hybrid Iterative Reconstruction, Model-Based Iterative Reconstruction, and Virtual Monoenergetic Reconstruction Images at Both Low- and Standard-Dose Settings in Measurement of Emphysema Volume and Airway Wall Thickness: A CT Phantom Study
por: Kim, Cherry, et al.
Publicado: (2018)

Myelolipomas of Both Adrenal Glands
por: Cha, Jai Seong, et al.
Publicado: (2011)

The Nocardia Rubra Cell Wall Skeleton Regulates Macrophages and Promotes Wound Healing
por: Hu, Kai, et al.
Publicado: (2022)

NLRP3 Inflammasome and Host Protection against Bacterial Infection
por: Kim, Jwa-Jin, et al.
Publicado: (2013)

Alum Adjuvant Enhances Protection against Respiratory Syncytial Virus but Exacerbates Pulmonary Inflammation by Modulating Multiple Innate and Adaptive Immune Cells
por: Kim, Ki-Hye, et al.
Publicado: (2015)

A successful treatment of hypercalcemia with zoledronic acid in a 15-year-old boy with acute lymphoblastic leukemia
por: Park, Hye-Jin, et al.
Publicado: (2016)

Deep-Learning-Based Stroke Screening Using Skeleton Data from Neurological Examination Videos
por: Lee, Taeho, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_925rkp0pr6b9i72focjhnuj27m