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Current Challenges of Cardiac Amyloidosis Awareness among Romanian Cardiologists

Cardiac amyloidosis (CA) is a restrictive cardiomyopathy characterized by deposition of amyloid in the myocardium and recent studies revealed it is more frequently seen than we thought. Advances in diagnosis and treatment have been made over the last few years that make it desirable to diagnose CA w...

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Autores principales: Adam, Robert, Neculae, Gabriela, Stan, Claudiu, Jurcut, Ruxandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148147/
https://www.ncbi.nlm.nih.gov/pubmed/34066384
http://dx.doi.org/10.3390/diagnostics11050834
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author Adam, Robert
Neculae, Gabriela
Stan, Claudiu
Jurcut, Ruxandra
author_facet Adam, Robert
Neculae, Gabriela
Stan, Claudiu
Jurcut, Ruxandra
author_sort Adam, Robert
collection PubMed
description Cardiac amyloidosis (CA) is a restrictive cardiomyopathy characterized by deposition of amyloid in the myocardium and recent studies revealed it is more frequently seen than we thought. Advances in diagnosis and treatment have been made over the last few years that make it desirable to diagnose CA without delay, and that may require extra education. An online survey was conducted among cardiologists from Romania, representing the first assessment of the knowledge of CA among them, with 195 cardiologists answering the questionnaire. There was a wide variation in their knowledge regarding CA. Our participants had limited experience with CA and reported a significant delay between first cardiac symptoms and diagnosis. We address the gaps in knowledge that were identified as educational opportunities in the main identified areas: prevalence and treatment of wild type transthyretin amyloidosis (ATTRwt), prevalence of variant transthyretin amyloidosis (ATTRv) in Romania, diagnosis of CA, the delay in CA diagnosis and available treatment options. Awareness among cardiologists is the most important challenge in diagnosing CA. Romanian cardiologists are partially aware of this topic, but there are still gaps in their knowledge. Educational programs can improve screening of patients with a high suspicion for this progressive condition the prognosis of which has been dramatically changed by the new treatment options.
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spelling pubmed-81481472021-05-26 Current Challenges of Cardiac Amyloidosis Awareness among Romanian Cardiologists Adam, Robert Neculae, Gabriela Stan, Claudiu Jurcut, Ruxandra Diagnostics (Basel) Article Cardiac amyloidosis (CA) is a restrictive cardiomyopathy characterized by deposition of amyloid in the myocardium and recent studies revealed it is more frequently seen than we thought. Advances in diagnosis and treatment have been made over the last few years that make it desirable to diagnose CA without delay, and that may require extra education. An online survey was conducted among cardiologists from Romania, representing the first assessment of the knowledge of CA among them, with 195 cardiologists answering the questionnaire. There was a wide variation in their knowledge regarding CA. Our participants had limited experience with CA and reported a significant delay between first cardiac symptoms and diagnosis. We address the gaps in knowledge that were identified as educational opportunities in the main identified areas: prevalence and treatment of wild type transthyretin amyloidosis (ATTRwt), prevalence of variant transthyretin amyloidosis (ATTRv) in Romania, diagnosis of CA, the delay in CA diagnosis and available treatment options. Awareness among cardiologists is the most important challenge in diagnosing CA. Romanian cardiologists are partially aware of this topic, but there are still gaps in their knowledge. Educational programs can improve screening of patients with a high suspicion for this progressive condition the prognosis of which has been dramatically changed by the new treatment options. MDPI 2021-05-06 /pmc/articles/PMC8148147/ /pubmed/34066384 http://dx.doi.org/10.3390/diagnostics11050834 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Adam, Robert
Neculae, Gabriela
Stan, Claudiu
Jurcut, Ruxandra
Current Challenges of Cardiac Amyloidosis Awareness among Romanian Cardiologists
title Current Challenges of Cardiac Amyloidosis Awareness among Romanian Cardiologists
title_full Current Challenges of Cardiac Amyloidosis Awareness among Romanian Cardiologists
title_fullStr Current Challenges of Cardiac Amyloidosis Awareness among Romanian Cardiologists
title_full_unstemmed Current Challenges of Cardiac Amyloidosis Awareness among Romanian Cardiologists
title_short Current Challenges of Cardiac Amyloidosis Awareness among Romanian Cardiologists
title_sort current challenges of cardiac amyloidosis awareness among romanian cardiologists
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148147/
https://www.ncbi.nlm.nih.gov/pubmed/34066384
http://dx.doi.org/10.3390/diagnostics11050834
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