Cargando…

Anti-Inflammatory Effects of Dietary Plant Stanol Supplementation Are Largely Dependent on the Intake of Cholesterol in a Mouse Model of Metabolic Inflammation

The prevalence of metabolic disorders characterized by chronic inflammation has been on a sharp rise for decades. As such, tools that address metabolic and inflammatory dysregulation are of great importance. Plant stanols are well-known for reducing intestinal cholesterol absorption and may also hav...

Descripción completa

Detalles Bibliográficos
Autores principales:	Magro dos Reis, Inês, Houben, Tom, Gijbels, Marion J. J., Lütjohann, Dieter, Plat, Jogchum, Shiri-Sverdlov, Ronit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148209/ https://www.ncbi.nlm.nih.gov/pubmed/34066407 http://dx.doi.org/10.3390/biomedicines9050518

Ejemplares similares

Comment on Tauriainen et al.: Serum, liver and bile sitosterol and sitostanol in obese patients with and without NAFLD
por: Plat, Jogchum, et al.
Publicado: (2018)

Effects of Dietary Plant Sterols and Stanol Esters with Low- and High-Fat Diets in Chronic and Acute Models for Experimental Colitis
por: te Velde, Anje A., et al.
Publicado: (2015)

Protective Role of Plant Sterol and Stanol Esters in Liver Inflammation: Insights from Mice and Humans
por: Plat, Jogchum, et al.
Publicado: (2014)

Acute Intake of Plant Stanol Esters Induces Changes in Lipid and Lipoprotein Metabolism-Related Gene Expression in the Liver and Intestines of Mice
por: De Smet, Els, et al.
Publicado: (2015)

Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment
por: Houben, Tom, et al.
Publicado: (2021)

Cathepsin D regulates lipid metabolism in murine steatohepatitis
por: Houben, Tom, et al.
Publicado: (2017)

Sex‐opposed inflammatory effects of 27‐hydroxycholesterol are mediated via differences in estrogen signaling
por: Houben, Tom, et al.
Publicado: (2020)

Plant Stanol Esters Lower Serum Triacylglycerol Concentrations via a Reduced Hepatic VLDL-1 Production
por: Plat, Jogchum, et al.
Publicado: (2009)

Effects of a Plant Sterol or Stanol Enriched Mixed Meal on Postprandial Lipid Metabolism in Healthy Subjects
por: Baumgartner, Sabine, et al.
Publicado: (2016)

Serum Low Density Lipoprotein Cholesterol Concentration Is Not Dependent on Cholesterol Synthesis and Absorption in Healthy Humans
por: Stellaard, Frans, et al.
Publicado: (2022)

Pneumococcal Immunization Reduces Neurological and Hepatic Symptoms in a Mouse Model for Niemann-Pick Type C1 Disease
por: Houben, Tom, et al.
Publicado: (2019)

Hematopoietic Npc1 mutation shifts gut microbiota composition in Ldlr(−/−) mice on a high-fat, high-cholesterol diet
por: Houben, Tom, et al.
Publicado: (2019)

Differential effects on inhibition of cholesterol absorption by plant stanol and plant sterol esters in apoE−/− mice
por: Weingärtner, Oliver, et al.
Publicado: (2011)

Non-Cholesterol Sterols in Breast Milk and Risk of Allergic Outcomes in the First Two Years of Life
por: van Brakel, Lieve, et al.
Publicado: (2022)

Internalization of Modified Lipids by CD36 and SR-A Leads to Hepatic Inflammation and Lysosomal Cholesterol Storage in Kupffer Cells
por: Bieghs, Veerle, et al.
Publicado: (2012)

Inhibition of Extracellular Cathepsin D Reduces Hepatic Lipid Accumulation and Leads to Mild Changes in Inflammationin NASH Mice
por: Yadati, Tulasi, et al.
Publicado: (2021)

Plasma fat-soluble vitamin and carotenoid concentrations after plant sterol and plant stanol consumption: a meta-analysis of randomized controlled trials
por: Baumgartner, Sabine, et al.
Publicado: (2016)

Decreasing the Cholesterol Burden in Heterozygous Familial Hypercholesterolemia Children by Dietary Plant Stanol Esters
por: Vuorio, Alpo, et al.
Publicado: (2018)

Blood-derived macrophages prone to accumulate lysosomal lipids trigger oxLDL-dependent murine hepatic inflammation
por: Houben, Tom, et al.
Publicado: (2017)

Plant Sterols and Plant Stanols in Cholesterol Management and Cardiovascular Prevention
por: Barkas, Fotios, et al.
Publicado: (2023)

A Transient Inflammatory Response Induced by Lipopolysaccharide Infusion Lowers Markers of Endogenous Cholesterol and Bile Acid Synthesis in Healthy Normocholesterolemic Young Men
por: Mashnafi, Sultan, et al.
Publicado: (2023)

Modelling approach to simulate reductions in LDL cholesterol levels after combined intake of statins and phytosterols/-stanols in humans
por: Eussen, Simone RBM, et al.
Publicado: (2011)

Short-term LDL cholesterol-lowering efficacy of plant stanol esters
por: Hallikainen, Maarit, et al.
Publicado: (2002)

Serum Cholesterol Reduction Efficacy of Biscuits with Added Plant Stanol Ester
por: Kriengsinyos, Wantanee, et al.
Publicado: (2015)

The Ins and Outs of Cathepsins: Physiological Function and Role in Disease Management
por: Yadati, Tulasi, et al.
Publicado: (2020)

Weekly Treatment of 2-Hydroxypropyl-β-cyclodextrin Improves Intracellular Cholesterol Levels in LDL Receptor Knockout Mice
por: Walenbergh, Sofie M. A., et al.
Publicado: (2015)

Cholesterol metabolism and serum non-cholesterol sterols: summary of 13 plant stanol ester interventions
por: Hallikainen, Maarit, et al.
Publicado: (2014)

LDL-Cholesterol Lowering of Plant Sterols and Stanols—Which Factors Influence Their Efficacy?
por: Trautwein, Elke A., et al.
Publicado: (2018)

LDL Receptor Knock-Out Mice Are a Physiological Model Particularly Vulnerable to Study the Onset of Inflammation in Non-Alcoholic Fatty Liver Disease
por: Bieghs, Veerle, et al.
Publicado: (2012)

The Influence of a Conjugated Pneumococcal Vaccination on Plasma Antibody Levels against Oxidized Low-Density Lipoprotein in Metabolic Disease Patients: A Single-Arm Pilot Clinical Trial
por: Shiri-Sverdlov, Ronit, et al.
Publicado: (2021)

Cholesterol Lowering Effect of Plant Stanol Ester Yoghurt Drinks with Added Camelina Oil
por: Salo, Pia, et al.
Publicado: (2016)

The effects of vitamin E or lipoic acid supplementation on oxyphytosterols in subjects with elevated oxidative stress: a randomized trial
por: Baumgartner, Sabine, et al.
Publicado: (2017)

Associations between SNPs in Intestinal Cholesterol Absorption and Endogenous Cholesterol Synthesis Genes with Cholesterol Metabolism
por: Schroor, Maite M., et al.
Publicado: (2021)

Non-Cholesterol Sterol Concentrations as Biomarkers for Cholesterol Absorption and Synthesis in Different Metabolic Disorders: A Systematic Review
por: Mashnafi, Sultan, et al.
Publicado: (2019)

Plant sterols/stanols as cholesterol lowering agents: A meta-analysis of randomized controlled trials
por: AbuMweis, Suhad S., et al.
Publicado: (2008)

P02.88. Powdered Red Yeast Rice and Plant Stanols and Sterols to lower cholesterol
por: Feuerstein, J, et al.
Publicado: (2012)

Dose-dependent LDL-cholesterol lowering effect by plant stanol ester consumption: clinical evidence
por: Laitinen, Kirsi, et al.
Publicado: (2012)

Inflammatory Bowel Disease: A Stressed “Gut/Feeling”
por: Oligschlaeger, Yvonne, et al.
Publicado: (2019)

Plasma cathepsin D correlates with histological classifications of fatty liver disease in adults and responds to intervention
por: Walenbergh, Sofie M. A., et al.
Publicado: (2016)

Macrophage Stimulating Protein Enhances Hepatic Inflammation in a NASH Model
por: Li, Jieyi, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_0hlk56p6c3r8mkfs6clg6pah4r