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Early Dysfunction of Substantia Nigra Dopamine Neurons in the ParkinQ311X Mouse
Mutations in the PARK2 gene encoding the protein parkin cause autosomal recessive juvenile parkinsonism (ARJP), a neurodegenerative disease characterized by early dysfunction and loss of dopamine (DA) neurons in the substantia nigra pars compacta (SNc). No therapy is currently available to prevent o...
Autores principales: | Regoni, Maria, Zanetti, Letizia, Comai, Stefano, Mercatelli, Daniela, Novello, Salvatore, Albanese, Federica, Croci, Laura, Consalez, Gian Giacomo, Ciammola, Andrea, Valtorta, Flavia, Morari, Michele, Sassone, Jenny |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148213/ https://www.ncbi.nlm.nih.gov/pubmed/34063112 http://dx.doi.org/10.3390/biomedicines9050514 |
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