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Early Dysfunction of Substantia Nigra Dopamine Neurons in the ParkinQ311X Mouse

Mutations in the PARK2 gene encoding the protein parkin cause autosomal recessive juvenile parkinsonism (ARJP), a neurodegenerative disease characterized by early dysfunction and loss of dopamine (DA) neurons in the substantia nigra pars compacta (SNc). No therapy is currently available to prevent o...

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Detalles Bibliográficos
Autores principales: Regoni, Maria, Zanetti, Letizia, Comai, Stefano, Mercatelli, Daniela, Novello, Salvatore, Albanese, Federica, Croci, Laura, Consalez, Gian Giacomo, Ciammola, Andrea, Valtorta, Flavia, Morari, Michele, Sassone, Jenny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148213/
https://www.ncbi.nlm.nih.gov/pubmed/34063112
http://dx.doi.org/10.3390/biomedicines9050514

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