Cargando…

The human papillomavirus oncoproteins: a review of the host pathways targeted on the road to transformation

Persistent infection with high-risk human papillomaviruses (HR-HPVs) is the causal factor in over 99 % of cervical cancer cases, and a significant proportion of oropharyngeal and anogenital cancers. The key drivers of HPV-mediated transformation are the oncoproteins E5, E6 and E7. Together, they act...

Descripción completa

Detalles Bibliográficos
Autores principales:	Scarth, James A., Patterson, Molly R., Morgan, Ethan L., Macdonald, Andrew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Microbiology Society 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148304/ https://www.ncbi.nlm.nih.gov/pubmed/33427604 http://dx.doi.org/10.1099/jgv.0.001540

Ejemplares similares

E6-mediated activation of JNK drives EGFR signalling to promote proliferation and viral oncoprotein expression in cervical cancer
por: Morgan, Ethan L., et al.
Publicado: (2020)

Subversion of Host Innate Immunity by Human Papillomavirus Oncoproteins
por: Lo Cigno, Irene, et al.
Publicado: (2020)

Human papillomavirus oncoproteins and apoptosis (Review)
por: JIANG, PEIYUE, et al.
Publicado: (2014)

Transforming activity of an oncoprotein-encoding circular RNA from human papillomavirus
por: Zhao, Jiawei, et al.
Publicado: (2019)

The deubiquitinase (DUB) USP13 promotes Mcl-1 stabilisation in cervical cancer
por: Morgan, Ethan L., et al.
Publicado: (2021)

Author Correction: Transforming activity of an oncoprotein-encoding circular RNA from human papillomavirus
por: Zhao, Jiawei, et al.
Publicado: (2022)

Targeting Human Papillomavirus-Associated Cancer by Oncoprotein-Specific Recombinant Antibodies
por: Donà, Maria Gabriella, et al.
Publicado: (2021)

Structural Insights in Multifunctional Papillomavirus Oncoproteins
por: Suarez, Irina, et al.
Publicado: (2018)

Modulation of microRNA-mRNA Target Pairs by Human Papillomavirus 16 Oncoproteins
por: Harden, Mallory E., et al.
Publicado: (2017)

Growth Dependence of Human Papillomavirus 16 DNA‐positive Cervical Cancer Cell Lines and Human Papillomavirus 16‐Transformed Human and Rat Cells on the Viral Oncoproteins
por: Watanabe, Sumie, et al.
Publicado: (1993)

Golgi Alkalinization by the Papillomavirus E5 Oncoprotein
por: Schapiro, Florencia, et al.
Publicado: (2000)

Discovery of reactive peptide inhibitors of human papillomavirus oncoprotein E6
por: Ye, Xiyun, et al.
Publicado: (2023)

Regulation of the Wnt/β-Catenin Signaling Pathway by Human Papillomavirus E6 and E7 Oncoproteins
por: Muñoz Bello, Jesus Omar, et al.
Publicado: (2015)

Papillomavirus E5: the smallest oncoprotein with many functions
por: Venuti, Aldo, et al.
Publicado: (2011)

Functions and modulation of PKM2 activity by human papillomavirus E7 oncoprotein (Review)
por: Gui, Chengzhi, et al.
Publicado: (2022)

Localisation of Human Papillomavirus 16 E7 Oncoprotein Changes with Cell Confluence
por: Laurson, Joanna, et al.
Publicado: (2011)

Phospholipidation of nuclear proteins by the human papillomavirus E6 oncoprotein: implication in carcinogenesis
por: Marx, Benjamin, et al.
Publicado: (2018)

Immunohistochemical Detection of Human Papillomavirus 16 E7 Oncoprotein in Cervical Lesions
por: Zhu, Jiang, et al.
Publicado: (2021)

Effects of human papillomavirus (HPV) type 16 oncoproteins on the expression of involucrin in human keratinocytes
por: Gyöngyösi, Eszter, et al.
Publicado: (2012)

Interaction of the Human Papillomavirus E6 Oncoprotein with Sorting Nexin 27 Modulates Endocytic Cargo Transport Pathways
por: Ganti, Ketaki, et al.
Publicado: (2016)

The human papillomavirus type 16 E7 oncoprotein targets Myc-interacting zinc-finger protein-1
por: Morandell, Dieter, et al.
Publicado: (2012)

Differential transforming activity of the retroviral Tax oncoproteins in human T lymphocytes
por: Ren, Tong, et al.
Publicado: (2013)

Intrabodies targeting human papillomavirus 16 E6 and E7 oncoproteins for therapy of established HPV-associated tumors
por: Paolini, Francesca, et al.
Publicado: (2021)

Coordinated oncogenic transformation and inhibition of host immune responses by the PAX3-FKHR fusion oncoprotein
por: Nabarro, Stephen, et al.
Publicado: (2005)

Human papillomavirus E6/E7 oncoproteins promote radiotherapy-mediated tumor suppression by globally hijacking host DNA damage repair
por: Bruyere, Diane, et al.
Publicado: (2023)

Human papillomavirus type 16 E7 oncoprotein mediates CCNA1 promoter methylation
por: Chalertpet, Kanwalat, et al.
Publicado: (2015)

Modulation of DNA methylation by human papillomavirus E6 and E7 oncoproteins in cervical cancer
por: Sen, Prakriti, et al.
Publicado: (2018)

Influence of Human Papillomavirus E7 Oncoprotein on Maturation and Function of Plasmacytoid Dendritic Cells In Vitro
por: Han, Rui, et al.
Publicado: (2018)

Werner Syndrome Protein (WRN) Regulates Cell Proliferation and the Human Papillomavirus 16 Life Cycle during Epithelial Differentiation
por: James, Claire D., et al.
Publicado: (2020)

Enhanced Intracellular Photosensitizer Uptake and Retention by Targeting Viral Oncoproteins in Human Papillomavirus Infected Cancer Cells and Cancer Stem Cells
por: Chizenga, Elvin Peter, et al.
Publicado: (2023)

Exploitation of ATP-sensitive potassium ion (K(ATP)) channels by HPV promotes cervical cancer cell proliferation by contributing to MAPK/AP-1 signalling
por: Scarth, James A., et al.
Publicado: (2023)

Increased expression of RRM2 by human papillomavirus E7 oncoprotein promotes angiogenesis in cervical cancer
por: Wang, N, et al.
Publicado: (2014)

Intracellular Analysis of the Interaction between the Human Papillomavirus Type 16 E6 Oncoprotein and Inhibitory Peptides
por: Stutz, Christina, et al.
Publicado: (2015)

Detection of Human Papillomavirus-16 E6-Oncoprotein in Epithelial Ovarian Tumors Samples of Iraqi Patients
por: Mahmood, Fahem Mohsin, et al.
Publicado: (2014)

Structural basis for recognition of the tumor suppressor protein PTPN14 by the oncoprotein E7 of human papillomavirus
por: Yun, Hye-Yeoung, et al.
Publicado: (2019)

Human papillomavirus 16 E7 oncoprotein alters the expression profiles of circular RNAs in Caski cells
por: Zheng, Si-Rong, et al.
Publicado: (2018)

The v-sis oncoprotein loses transforming activity when targeted to the early Golgi complex
Publicado: (1994)

Targeting of intracellular oncoproteins with peptide-centric CARs
por: Yarmarkovich, Mark, et al.
Publicado: (2023)

Molecular Analysis of the Interaction between Human PTPN21 and the Oncoprotein E7 from Human Papillomavirus Genotype 18
por: Lee, Hye Seon, et al.
Publicado: (2021)

Interaction between the human papillomavirus 16 E7 oncoprotein and gelsolin ignites cancer cell motility and invasiveness
por: Matarrese, Paola, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_523jgsr4lof4r73p2uu2pl1rgm