Kratom-Induced Liver Injury: A Case Series and Clinical Implications

Drug-induced liver injury (DILI) is among the most common causes of acute liver injury and acute liver failure in the United States. Kratom is an herbal supplement made from the leaves of a tropical evergreen tree (Mitragyna speciosa) that is native to Southeast Asia. Due to its psychotropic and opi...

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Autores principales: Botejue, Mahesh, Walia, Gurjot, Shahin, Omar, Sharma, Jyotsna, Zackria, Rasiq
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148389/
https://www.ncbi.nlm.nih.gov/pubmed/34055525
http://dx.doi.org/10.7759/cureus.14679
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author Botejue, Mahesh
Walia, Gurjot
Shahin, Omar
Sharma, Jyotsna
Zackria, Rasiq
author_facet Botejue, Mahesh
Walia, Gurjot
Shahin, Omar
Sharma, Jyotsna
Zackria, Rasiq
author_sort Botejue, Mahesh
collection PubMed
description Drug-induced liver injury (DILI) is among the most common causes of acute liver injury and acute liver failure in the United States. Kratom is an herbal supplement made from the leaves of a tropical evergreen tree (Mitragyna speciosa) that is native to Southeast Asia. Due to its psychotropic and opioid-like activity, there has been an increase in its use as a recreational drug. Despite this increase, little is known regarding the toxicities and adverse effects though it is known to cause DILI. We present two cases of DILI associated with Kratom use.
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spelling pubmed-81483892021-05-27 Kratom-Induced Liver Injury: A Case Series and Clinical Implications Botejue, Mahesh Walia, Gurjot Shahin, Omar Sharma, Jyotsna Zackria, Rasiq Cureus Internal Medicine Drug-induced liver injury (DILI) is among the most common causes of acute liver injury and acute liver failure in the United States. Kratom is an herbal supplement made from the leaves of a tropical evergreen tree (Mitragyna speciosa) that is native to Southeast Asia. Due to its psychotropic and opioid-like activity, there has been an increase in its use as a recreational drug. Despite this increase, little is known regarding the toxicities and adverse effects though it is known to cause DILI. We present two cases of DILI associated with Kratom use. Cureus 2021-04-25 /pmc/articles/PMC8148389/ /pubmed/34055525 http://dx.doi.org/10.7759/cureus.14679 Text en Copyright © 2021, Botejue et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Botejue, Mahesh
Walia, Gurjot
Shahin, Omar
Sharma, Jyotsna
Zackria, Rasiq
Kratom-Induced Liver Injury: A Case Series and Clinical Implications
title Kratom-Induced Liver Injury: A Case Series and Clinical Implications
title_full Kratom-Induced Liver Injury: A Case Series and Clinical Implications
title_fullStr Kratom-Induced Liver Injury: A Case Series and Clinical Implications
title_full_unstemmed Kratom-Induced Liver Injury: A Case Series and Clinical Implications
title_short Kratom-Induced Liver Injury: A Case Series and Clinical Implications
title_sort kratom-induced liver injury: a case series and clinical implications
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148389/
https://www.ncbi.nlm.nih.gov/pubmed/34055525
http://dx.doi.org/10.7759/cureus.14679
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