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Stability and optimal control strategies for a novel epidemic model of COVID-19
In this paper, a novel two-stage epidemic model with a dynamic control strategy is proposed to describe the spread of Corona Virus Disease 2019 (COVID-19) in China. Combined with local epidemic control policies, an epidemic model with a traceability process is established. We aim to investigate the...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148406/ https://www.ncbi.nlm.nih.gov/pubmed/34054221 http://dx.doi.org/10.1007/s11071-021-06524-x |
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author | Lü, Xing Hui, Hong-wen Liu, Fei-fei Bai, Ya-li |
author_facet | Lü, Xing Hui, Hong-wen Liu, Fei-fei Bai, Ya-li |
author_sort | Lü, Xing |
collection | PubMed |
description | In this paper, a novel two-stage epidemic model with a dynamic control strategy is proposed to describe the spread of Corona Virus Disease 2019 (COVID-19) in China. Combined with local epidemic control policies, an epidemic model with a traceability process is established. We aim to investigate the appropriate control strategies to minimize the control cost and ensure the normal operation of society under the premise of containing the epidemic. This work mainly includes: (i) propose the concept about the first and the second waves of COVID-19, as well as study the case data and regularity of four cities; (ii) derive the existence and stability of the equilibrium, the parameter sensitivity of the model, and the existence of the optimal control strategy; (iii) carry out the numerical simulation associated with the theoretical results and construct a dynamic control strategy and verify its feasibility. |
format | Online Article Text |
id | pubmed-8148406 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer Netherlands |
record_format | MEDLINE/PubMed |
spelling | pubmed-81484062021-05-26 Stability and optimal control strategies for a novel epidemic model of COVID-19 Lü, Xing Hui, Hong-wen Liu, Fei-fei Bai, Ya-li Nonlinear Dyn Original Paper In this paper, a novel two-stage epidemic model with a dynamic control strategy is proposed to describe the spread of Corona Virus Disease 2019 (COVID-19) in China. Combined with local epidemic control policies, an epidemic model with a traceability process is established. We aim to investigate the appropriate control strategies to minimize the control cost and ensure the normal operation of society under the premise of containing the epidemic. This work mainly includes: (i) propose the concept about the first and the second waves of COVID-19, as well as study the case data and regularity of four cities; (ii) derive the existence and stability of the equilibrium, the parameter sensitivity of the model, and the existence of the optimal control strategy; (iii) carry out the numerical simulation associated with the theoretical results and construct a dynamic control strategy and verify its feasibility. Springer Netherlands 2021-05-25 2021 /pmc/articles/PMC8148406/ /pubmed/34054221 http://dx.doi.org/10.1007/s11071-021-06524-x Text en © The Author(s), under exclusive licence to Springer Nature B.V. 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Original Paper Lü, Xing Hui, Hong-wen Liu, Fei-fei Bai, Ya-li Stability and optimal control strategies for a novel epidemic model of COVID-19 |
title | Stability and optimal control strategies for a novel epidemic model of COVID-19 |
title_full | Stability and optimal control strategies for a novel epidemic model of COVID-19 |
title_fullStr | Stability and optimal control strategies for a novel epidemic model of COVID-19 |
title_full_unstemmed | Stability and optimal control strategies for a novel epidemic model of COVID-19 |
title_short | Stability and optimal control strategies for a novel epidemic model of COVID-19 |
title_sort | stability and optimal control strategies for a novel epidemic model of covid-19 |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148406/ https://www.ncbi.nlm.nih.gov/pubmed/34054221 http://dx.doi.org/10.1007/s11071-021-06524-x |
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