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Stability and optimal control strategies for a novel epidemic model of COVID-19

In this paper, a novel two-stage epidemic model with a dynamic control strategy is proposed to describe the spread of Corona Virus Disease 2019 (COVID-19) in China. Combined with local epidemic control policies, an epidemic model with a traceability process is established. We aim to investigate the...

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Detalles Bibliográficos
Autores principales: Lü, Xing, Hui, Hong-wen, Liu, Fei-fei, Bai, Ya-li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148406/
https://www.ncbi.nlm.nih.gov/pubmed/34054221
http://dx.doi.org/10.1007/s11071-021-06524-x
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author Lü, Xing
Hui, Hong-wen
Liu, Fei-fei
Bai, Ya-li
author_facet Lü, Xing
Hui, Hong-wen
Liu, Fei-fei
Bai, Ya-li
author_sort Lü, Xing
collection PubMed
description In this paper, a novel two-stage epidemic model with a dynamic control strategy is proposed to describe the spread of Corona Virus Disease 2019 (COVID-19) in China. Combined with local epidemic control policies, an epidemic model with a traceability process is established. We aim to investigate the appropriate control strategies to minimize the control cost and ensure the normal operation of society under the premise of containing the epidemic. This work mainly includes: (i) propose the concept about the first and the second waves of COVID-19, as well as study the case data and regularity of four cities; (ii) derive the existence and stability of the equilibrium, the parameter sensitivity of the model, and the existence of the optimal control strategy; (iii) carry out the numerical simulation associated with the theoretical results and construct a dynamic control strategy and verify its feasibility.
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spelling pubmed-81484062021-05-26 Stability and optimal control strategies for a novel epidemic model of COVID-19 Lü, Xing Hui, Hong-wen Liu, Fei-fei Bai, Ya-li Nonlinear Dyn Original Paper In this paper, a novel two-stage epidemic model with a dynamic control strategy is proposed to describe the spread of Corona Virus Disease 2019 (COVID-19) in China. Combined with local epidemic control policies, an epidemic model with a traceability process is established. We aim to investigate the appropriate control strategies to minimize the control cost and ensure the normal operation of society under the premise of containing the epidemic. This work mainly includes: (i) propose the concept about the first and the second waves of COVID-19, as well as study the case data and regularity of four cities; (ii) derive the existence and stability of the equilibrium, the parameter sensitivity of the model, and the existence of the optimal control strategy; (iii) carry out the numerical simulation associated with the theoretical results and construct a dynamic control strategy and verify its feasibility. Springer Netherlands 2021-05-25 2021 /pmc/articles/PMC8148406/ /pubmed/34054221 http://dx.doi.org/10.1007/s11071-021-06524-x Text en © The Author(s), under exclusive licence to Springer Nature B.V. 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Original Paper
Lü, Xing
Hui, Hong-wen
Liu, Fei-fei
Bai, Ya-li
Stability and optimal control strategies for a novel epidemic model of COVID-19
title Stability and optimal control strategies for a novel epidemic model of COVID-19
title_full Stability and optimal control strategies for a novel epidemic model of COVID-19
title_fullStr Stability and optimal control strategies for a novel epidemic model of COVID-19
title_full_unstemmed Stability and optimal control strategies for a novel epidemic model of COVID-19
title_short Stability and optimal control strategies for a novel epidemic model of COVID-19
title_sort stability and optimal control strategies for a novel epidemic model of covid-19
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148406/
https://www.ncbi.nlm.nih.gov/pubmed/34054221
http://dx.doi.org/10.1007/s11071-021-06524-x
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