A Novel Approach for a Chip-Sized Scanning Optical Microscope

The recent advances in chip-size microscopy based on optical scanning with spatially resolved nano-illumination light sources are presented. This new straightforward technique takes advantage of the currently achieved miniaturization of LEDs in fully addressable arrays. These nano-LEDs are used to s...

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Autores principales: Canals, Joan, Franch, Nil, Moro, Victor, Moreno, Sergio, Prades, Juan Daniel, Romano-Rodríguez, Albert, Bornemann, Steffen, Bezshlyakh, Daria D., Waag, Andreas, Vogelbacher, Florian, Schrittwieser, Stefan, Kluczyk-Korch, Katarzyna, Auf der Maur, Matthias, Di Carlo, Aldo, Diéguez, Angel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148435/
https://www.ncbi.nlm.nih.gov/pubmed/34066638
http://dx.doi.org/10.3390/mi12050527
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author Canals, Joan
Franch, Nil
Moro, Victor
Moreno, Sergio
Prades, Juan Daniel
Romano-Rodríguez, Albert
Bornemann, Steffen
Bezshlyakh, Daria D.
Waag, Andreas
Vogelbacher, Florian
Schrittwieser, Stefan
Kluczyk-Korch, Katarzyna
Auf der Maur, Matthias
Di Carlo, Aldo
Diéguez, Angel
author_facet Canals, Joan
Franch, Nil
Moro, Victor
Moreno, Sergio
Prades, Juan Daniel
Romano-Rodríguez, Albert
Bornemann, Steffen
Bezshlyakh, Daria D.
Waag, Andreas
Vogelbacher, Florian
Schrittwieser, Stefan
Kluczyk-Korch, Katarzyna
Auf der Maur, Matthias
Di Carlo, Aldo
Diéguez, Angel
author_sort Canals, Joan
collection PubMed
description The recent advances in chip-size microscopy based on optical scanning with spatially resolved nano-illumination light sources are presented. This new straightforward technique takes advantage of the currently achieved miniaturization of LEDs in fully addressable arrays. These nano-LEDs are used to scan the sample with a resolution comparable to the LED sizes, giving rise to chip-sized scanning optical microscopes without mechanical parts or optical accessories. The operation principle and the potential of this new kind of microscope are analyzed through three different implementations of decreasing LED dimensions from 20 µm down to 200 nm.
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spelling pubmed-81484352021-05-26 A Novel Approach for a Chip-Sized Scanning Optical Microscope Canals, Joan Franch, Nil Moro, Victor Moreno, Sergio Prades, Juan Daniel Romano-Rodríguez, Albert Bornemann, Steffen Bezshlyakh, Daria D. Waag, Andreas Vogelbacher, Florian Schrittwieser, Stefan Kluczyk-Korch, Katarzyna Auf der Maur, Matthias Di Carlo, Aldo Diéguez, Angel Micromachines (Basel) Article The recent advances in chip-size microscopy based on optical scanning with spatially resolved nano-illumination light sources are presented. This new straightforward technique takes advantage of the currently achieved miniaturization of LEDs in fully addressable arrays. These nano-LEDs are used to scan the sample with a resolution comparable to the LED sizes, giving rise to chip-sized scanning optical microscopes without mechanical parts or optical accessories. The operation principle and the potential of this new kind of microscope are analyzed through three different implementations of decreasing LED dimensions from 20 µm down to 200 nm. MDPI 2021-05-06 /pmc/articles/PMC8148435/ /pubmed/34066638 http://dx.doi.org/10.3390/mi12050527 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Canals, Joan
Franch, Nil
Moro, Victor
Moreno, Sergio
Prades, Juan Daniel
Romano-Rodríguez, Albert
Bornemann, Steffen
Bezshlyakh, Daria D.
Waag, Andreas
Vogelbacher, Florian
Schrittwieser, Stefan
Kluczyk-Korch, Katarzyna
Auf der Maur, Matthias
Di Carlo, Aldo
Diéguez, Angel
A Novel Approach for a Chip-Sized Scanning Optical Microscope
title A Novel Approach for a Chip-Sized Scanning Optical Microscope
title_full A Novel Approach for a Chip-Sized Scanning Optical Microscope
title_fullStr A Novel Approach for a Chip-Sized Scanning Optical Microscope
title_full_unstemmed A Novel Approach for a Chip-Sized Scanning Optical Microscope
title_short A Novel Approach for a Chip-Sized Scanning Optical Microscope
title_sort novel approach for a chip-sized scanning optical microscope
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148435/
https://www.ncbi.nlm.nih.gov/pubmed/34066638
http://dx.doi.org/10.3390/mi12050527
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