Cargando…
Ixekizumab May Improve Renal Function in Psoriasis
Background: Psoriasis is a chronic dermatological condition characterized by lesions on extensor surfaces, hands, feet, and genital areas. Chronic renal failure is often associated with metabolic syndrome and inflammatory conditions, such as psoriasis. Case report: In this paper, we report a patient...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148436/ https://www.ncbi.nlm.nih.gov/pubmed/34066917 http://dx.doi.org/10.3390/healthcare9050543 |
_version_ | 1783697837463175168 |
---|---|
author | Amoruso, Giuseppe Fabrizio Nisticò, Steven Paul Iannone, Luigi Russo, Emilio Rago, Giuseppe Patruno, Cataldo Bennardo, Luigi |
author_facet | Amoruso, Giuseppe Fabrizio Nisticò, Steven Paul Iannone, Luigi Russo, Emilio Rago, Giuseppe Patruno, Cataldo Bennardo, Luigi |
author_sort | Amoruso, Giuseppe Fabrizio |
collection | PubMed |
description | Background: Psoriasis is a chronic dermatological condition characterized by lesions on extensor surfaces, hands, feet, and genital areas. Chronic renal failure is often associated with metabolic syndrome and inflammatory conditions, such as psoriasis. Case report: In this paper, we report a patient with stage-three chronic renal failure that improved his renal condition after treatment with ixekizumab, an anti-IL17A drug used in the treatment of various cutaneous and rheumatological conditions. Conclusions: IL17A blockage may help to treat various autoimmune and inflammatory conditions, such as psoriasis, that may lead to renal impairment. Further investigation is necessary in order to prove the effectiveness of this drug in renal conditions. |
format | Online Article Text |
id | pubmed-8148436 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-81484362021-05-26 Ixekizumab May Improve Renal Function in Psoriasis Amoruso, Giuseppe Fabrizio Nisticò, Steven Paul Iannone, Luigi Russo, Emilio Rago, Giuseppe Patruno, Cataldo Bennardo, Luigi Healthcare (Basel) Case Report Background: Psoriasis is a chronic dermatological condition characterized by lesions on extensor surfaces, hands, feet, and genital areas. Chronic renal failure is often associated with metabolic syndrome and inflammatory conditions, such as psoriasis. Case report: In this paper, we report a patient with stage-three chronic renal failure that improved his renal condition after treatment with ixekizumab, an anti-IL17A drug used in the treatment of various cutaneous and rheumatological conditions. Conclusions: IL17A blockage may help to treat various autoimmune and inflammatory conditions, such as psoriasis, that may lead to renal impairment. Further investigation is necessary in order to prove the effectiveness of this drug in renal conditions. MDPI 2021-05-07 /pmc/articles/PMC8148436/ /pubmed/34066917 http://dx.doi.org/10.3390/healthcare9050543 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Amoruso, Giuseppe Fabrizio Nisticò, Steven Paul Iannone, Luigi Russo, Emilio Rago, Giuseppe Patruno, Cataldo Bennardo, Luigi Ixekizumab May Improve Renal Function in Psoriasis |
title | Ixekizumab May Improve Renal Function in Psoriasis |
title_full | Ixekizumab May Improve Renal Function in Psoriasis |
title_fullStr | Ixekizumab May Improve Renal Function in Psoriasis |
title_full_unstemmed | Ixekizumab May Improve Renal Function in Psoriasis |
title_short | Ixekizumab May Improve Renal Function in Psoriasis |
title_sort | ixekizumab may improve renal function in psoriasis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148436/ https://www.ncbi.nlm.nih.gov/pubmed/34066917 http://dx.doi.org/10.3390/healthcare9050543 |
work_keys_str_mv | AT amorusogiuseppefabrizio ixekizumabmayimproverenalfunctioninpsoriasis AT nisticostevenpaul ixekizumabmayimproverenalfunctioninpsoriasis AT iannoneluigi ixekizumabmayimproverenalfunctioninpsoriasis AT russoemilio ixekizumabmayimproverenalfunctioninpsoriasis AT ragogiuseppe ixekizumabmayimproverenalfunctioninpsoriasis AT patrunocataldo ixekizumabmayimproverenalfunctioninpsoriasis AT bennardoluigi ixekizumabmayimproverenalfunctioninpsoriasis |