Biochemical characterization of adenosine deaminase (CD26; EC 3.5.4.4) activity in human lymphocyte-rich peripheral blood mononuclear cells

The conversion of adenosine to inosine is catalyzed by adenosine deaminase (ADA) (EC 3.5.4.4), which has two isoforms in humans (ADA1 and ADA2) and belongs to the zinc-dependent hydrolase family. ADA modulates lymphocyte function and differentiation, and regulates inflammatory and immune responses....

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Detalles Bibliográficos
Autores principales: Costa, L.R., de Souza, A.K.Y., Scholl, J.N., Figueiró, F., Battastini, A.M.O., Jaques, J.A. dos Santos, Zanoelo, F.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148981/
https://www.ncbi.nlm.nih.gov/pubmed/34037096
http://dx.doi.org/10.1590/1414-431X2020e10850

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