An open-label randomized controlled trial of the effect of lopinavir/ritonavir, lopinavir/ritonavir plus IFN-β-1a and hydroxychloroquine in hospitalized patients with COVID-19

OBJECTIVES: We evaluated the clinical, virological and safety outcomes of lopinavir/ritonavir, lopinavir/ritonavir–interferon (IFN)-β-1a, hydroxychloroquine or remdesivir in comparison to standard of care (control) in coronavirus 2019 disease (COVID-19) inpatients requiring oxygen and/or ventilatory...

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Detalles Bibliográficos
Autores principales: Ader, Florence, Peiffer-Smadja, Nathan, Poissy, Julien, Bouscambert-Duchamp, Maude, Belhadi, Drifa, Diallo, Alpha, Delmas, Christelle, Saillard, Juliette, Dechanet, Aline, Mercier, Noémie, Dupont, Axelle, Alfaiate, Toni, Lescure, François-Xavier, Raffi, François, Goehringer, François, Kimmoun, Antoine, Jaureguiberry, Stéphane, Reignier, Jean, Nseir, Saad, Danion, François, Clere-Jehl, Raphael, Bouiller, Kévin, Navellou, Jean-Christophe, Tolsma, Violaine, Cabié, André, Dubost, Clément, Courjon, Johan, Leroy, Sylvie, Mootien, Joy, Gaci, Rostane, Mourvillier, Bruno, Faure, Emmanuel, Pourcher, Valérie, Gallien, Sébastien, Launay, Odile, Lacombe, Karine, Lanoix, Jean-Philippe, Makinson, Alain, Martin-Blondel, Guillaume, Bouadma, Lila, Botelho-Nevers, Elisabeth, Gagneux-Brunon, Amandine, Epaulard, Olivier, Piroth, Lionel, Wallet, Florent, Richard, Jean-Christophe, Reuter, Jean, Staub, Thérèse, Lina, Bruno, Noret, Marion, Andrejak, Claire, Lê, Minh Patrick, Peytavin, Gilles, Hites, Maya, Costagliola, Dominique, Yazdanpanah, Yazdan, Burdet, Charles, Mentré, France
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149166/
https://www.ncbi.nlm.nih.gov/pubmed/34048876
http://dx.doi.org/10.1016/j.cmi.2021.05.020

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