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Entrectinib: A Review in NTRK+ Solid Tumours and ROS1+ NSCLC
Entrectinib (Rozlytrek(®)) is an orally active, CNS-penetrant, small-molecule, selective inhibitor of the tropomyosin receptor tyrosine kinases TRKA/B/C [encoded by the neurotrophic tyrosine receptor kinase (NTRK) genes NTRK1/2/3, respectively], the proto-oncogene tyrosine-protein kinase ROS1 (ROS1)...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer International Publishing
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149347/ https://www.ncbi.nlm.nih.gov/pubmed/33871816 http://dx.doi.org/10.1007/s40265-021-01503-3 |